Maxillary Cuniculatum Carcinoma: a Case Report and Literature Review

Sepúlveda, Ilson; Spencer, Loreto; Platín, Enrique

doi:10.4067/s0718-381x2012000300006

Cited by 8 publications

(17 citation statements)

References 6 publications

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“…Human papilloma virus (HPV; types 1-4, 6, 11, and 18) were also detected in certain cases but results were insignificant [7,8]. Therefore, the exact etiology is not well established [6]. However, in the present case, the patient had no adverse oral habits.…”

Section: Discussionmentioning

confidence: 58%

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Carcinoma Cuniculatum of the Alveolar Mucosa: A Rare Variant of Squamous Cell Carcinoma

Sivapathasundharam

Kavitha

Padmapriya

2018

Head and Neck Pathol

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Carcinoma cuniculatum is one of the variants of squamous cell carcinoma. It is significantly rare with an incidence rate < 1% compared to other histological variants of squamous cell carcinoma. Various etiologic factors implicated are trauma, HPV, chronic inflammation and alcohol consumption but real causative agent still remains unclear. Initially it resembles plantar wart which slowly progress to bulky exophytic mass in the sole of the foot, where cases have been reported first. In the oral cavity it presents clinically as an exophytic growth and slowly invades the jaw and destroys the underlying bone. Microscopically it exhibits as both exophytic and endophytic epithelial masses along with well differentiated and pronounced hyperkeratosis. Treatment includes surgical resection alone unlike other variants which are treated by radiation with or without chemotherapy. Here we present a case of carcinoma cuniculatum occurred in alveolar mucosa of a 47 years old female. It presented as an exophytic growth in mandibular alveolar region, with histological features consistent with carcinoma cuniculatum.

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Section: Discussionmentioning

confidence: 58%

“…Our case occurred in female patient which is comparatively rare. Etiological factors include trauma, tobacco, alcohol and chronic inflammation [6]. Human papilloma virus (HPV; types 1-4, 6, 11, and 18) were also detected in certain cases but results were insignificant [7,8].…”

Section: Discussionmentioning

confidence: 99%

Carcinoma Cuniculatum of the Alveolar Mucosa: A Rare Variant of Squamous Cell Carcinoma

Sivapathasundharam

Kavitha

Padmapriya

2018

Head and Neck Pathol

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“…A high degree of suspicion along with a close working relationship between the treating physician, pathologist and radiologist is required to arrive at the diagnosis. [ 2 ]…”

Section: Discussionmentioning

confidence: 99%

“…The extensive osteolysis resembled a rabbit burrow involving the entire maxilla from the right to the left, confirming the diagnosis of CC was made [ Figure 7 ]. [ 1 2 ]…”

Section: Case Reportmentioning

confidence: 99%

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Proliferative endophytic lesion of the maxilla: A diagnostic challenge

Prasad

Moorthy

Bhadranna³

et al. 2018

J Oral Maxillofac Pathol

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Carcinoma cuniculatum (CC) is an extremely rare neoplasm of the oral cavity. It is essentially a well-differentiated variety of squamous cell carcinoma and shows lower metastasis risk. The histological features of CC can mimic that of papillary squamous cell carcinoma or verrucous carcinoma. CC commonly affects the plantar region of the foot, and very few cases have been described in the oral cavity. The classical histological characteristics noted are infiltration of underlying connective tissue by squamous epithelium with keratin cores and keratin-filled crypts. Herewith, we present a case of CC of the right maxilla in a young Dravidian male patient who works in a battery factory. The case presented a diagnostic challenge both clinically and histopathologically before it was completely resected using a total maxillectomy technique. The case delineates the diagnostic challenge and management of the disease.

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Cuneiform (cuniculatum) variant of oral squamous cell carcinoma revisited: Presentation of two cases and literature review of a rare entity

et al. 2022

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Background Oral carcinoma cuniculatum (OCC) is a rare, locally aggressive tumor, which tends to invade underlying bone. We present two cases of OCC, one demonstrating invasion of the mandible and the other limited to the tongue. Methods An 87‐year‐old male presented with a right‐sided buccogingival lesion. Biopsy results led to a diagnosis of verrucous hyperplasia, which was later revised to OCC. Additionally, a 94‐year‐old female presented with a left lateral tongue lesion. A biopsy showed in‐situ and invasive keratinizing squamous cell carcinoma that was later defined as a soft tissue OCC. Results Following surgical resection, the diagnosis of OCC was established in both patients. We provide a comprehensive literature review of OCC in the context of both case presentations. Conclusions OCC is a rare entity, which has a tendency to be misdiagnosed. We emphasize the importance of recognizing the common features of OCC in order to aid in accurate diagnosis.

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Maxillary Cuniculatum Carcinoma: a Case Report and Literature Review

Cited by 8 publications

References 6 publications

Carcinoma Cuniculatum of the Alveolar Mucosa: A Rare Variant of Squamous Cell Carcinoma

Carcinoma Cuniculatum of the Alveolar Mucosa: A Rare Variant of Squamous Cell Carcinoma

Proliferative endophytic lesion of the maxilla: A diagnostic challenge

Cuneiform (cuniculatum) variant of oral squamous cell carcinoma revisited: Presentation of two cases and literature review of a rare entity

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