Maxillary sinus fusariosis in immunocompetent hosts

Abstract

We report the first known cases of Fusariosis of maxillary sinus with granuloma and oro-antral fistula in two immunocompetent hosts. Fusarium solani was demonstrated in the direct microscopic examination and isolated in heavy growth from the biopsy materials. Both these patients were successfully treated with oral ketoconazole (200 mg daily) for three weeks followed by a Caldwell-Luc operation. Ketoconazole was continued for two months post-operatively.

Fusarium Infections in Immunocompromised Patients

“…Peritonitis in patients receiving continuous ambulatory peritoneal dialysis has also been described (34,52,92). Other infections in immunocompetent patients include sinusitis (56), pneumonia (62,97), thrombophlebitis (69), fungemia with or without organ involvement (74,104), endophtalmitis (35,86), septic arthritis (51), and osteomyelitis (10). Two recent outbreaks of fusarial keratitis were recently described in the United States (164 cases) and Singapore (66 cases).…”

“…may cause allergic sinusitis (111) or chronic noninvasive or invasive sinusitis (56,103). By contrast, sinusitis is always invasive in immunocompromised hosts (60,99,108).…”

Iatrogenic transposition of the Parotid duct into the maxillary sinus after tooth extraction and closure of an oroantral fistula. A case report

“…Other causes are dentoalveolar infections (Felix et al, 1991;Kurien et al, 1992;Güven 1998), destruction of the maxillary sinus floor by cysts or benign or malignant tumors (Chaudhuri, 1975;Babajews, 1986;Güven, 1998), Paget's disease (McMahon and Tzadok, 1986), trauma (Norman, 1977), complications of the CaldwelleLuc procedure (De Freitas and Lucente, 1988) and dental implant surgery (Anavi et al, 2003).…”

Hyalohyphomycosis: Infection Due to Hyaline Moulds

“…A hospital outbreak of F. verticillioides fungemia in immunocompetent patients has been recently reported [12]. Other infections include sinusitis, pneumonia, cutaneous and subcutaneous infections, septic arthritis, and osteomyelitis [13][14][15][16][17].…”