Maximization of bioconversion of castor oil into ricinoleic acid by response surface methodology

Goswami, Diganta; Sen, Ramkrishna; Basu, Jayanta Kumar; De, Sirshendu

doi:10.1016/j.biortech.2008.11.040

Cited by 34 publications

(24 citation statements)

References 20 publications

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“…The application of RSM contributes to the rapid screening of experimental factors and factors interactions, thus obtaining the optimal process parameters, which significantly reduces the cost of experimentation (Ghosh and Hallenbeck, 2010). Moreover, this method has been extensively used to optimize the operational conditions of bioconversion process (Goswami et al, 2009;Liu et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

Optimization of biotransformation from phytosterol to androstenedione by a mutant Mycobacterium neoaurum ZJUVN-08

Zhang

Peng

et al. 2013

J. Zhejiang Univ. Sci. B

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Biotransformation of phytosterol (PS) by a newly isolated mutant Mycobacterium neoaurum ZJUVN-08 to produce androstenedione has been investigated in this paper. The parameters of the biotransformation process were optimized using fractional factorial design and response surface methodology. Androstenedione was the sole product in the fermentation broth catalyzed by the mutant M. neoaurum ZJUVN-08 strain. Results showed that molar ratio of hydroxypropyl-β-cyclodextrin (HP-β-CD) to PS and substrate concentrations were the two most significant factors affecting androstenedione production. By analyzing the statistical model of three-dimensional surface plot, the optimal process conditions were observed at 0.1 g/L inducer, pH 7.0, molar ratio of HP-β-CD to PS 1.92:1, 8.98 g/L PS, and at 120 h of incubation time. Under these conditions, the maximum androstenedione yield was 5.96 g/L and nearly the same with the non-optimized (5.99 g/L), while the maximum PS conversion rate was 94.69% which increased by 10.66% compared with the non-optimized (84.03%). The predicted optimum conditions from the mathematical model were in agreement with the verification experimental results. It is considered that response surface methodology was a powerful and efficient method to optimize the parameters of PS biotransformation process.

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Section: Introductionmentioning

confidence: 99%

Optimization of biotransformation from phytosterol to androstenedione by a mutant Mycobacterium neoaurum ZJUVN-08

Zhang

Peng

et al. 2013

J. Zhejiang Univ. Sci. B

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“…The response variable had a quadratic response (p-value 0,001), in which both pressure and temperature showed an effect, and had a quadratic relationship. According to the Equation (1) and Table 4, all the terms proposed are significant (p-value <0,05), opposed to the results obtained in a study conducted by Goswami et al, (2009). This research seeks to optimize bioconversion of castor bean oil into ricinoleic acid, finding an equation that characterizes that process.…”

Section: Response Surface Methodologymentioning

confidence: 95%

Optimization of castor seed oil extraction process using response surface methodology

Mosquera¹

2016

ing.inv.

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This work focuses on the study of the oil extraction yield from castor seed using three different seed conditions: whole, minced and bare endosperm. Taguchi design was used to determine the contribution of the following parameters: seed condition, seed load in the extractor, temperature, and pressure. It was proved that it is necessary to introduce the whole seed and that the presence of the pericarp increases the extraction yield. The contribution of the control factors has an extraction yield limit. After determining which factors contributed to the process, these were left at their optimum levels aiming to reduce the control factors to only two. The complete analysis was done using a surface response methodology giving the best parameter for temperature and pressure that allows a better yielding mechanical extraction. The oil extraction yield can be kept up to 35 % of the seed. Keywords: Experiment design, mechanical extraction, Ricinus communis L. RESUMENEste trabajo se centra en el estudio de la extracción y la producción de aceite de semillas de ricino usando tres diferentes estados de semillas: entera, partida y sin testa. Se utilizó un diseño Taguchi para determinar la contribución de los siguientes parámetros: estado de las semillas, cantidad de semilla en el extractor, temperatura y presión. Se demostró que es necesario introducir la semilla entera para aumentar el rendimiento de la extracción. La contribución de los factores de control tiene un límite de extracción en la variable respuesta (rendimiento). Después de determinar cuáles factores contribuían altamente al proceso de extracción y cuáles no, se procedió a dejarlos en los niveles de mayor contribución con la finalidad de reducir el número de factores de control a dos. Posteriormente se utilizó la metodología de superficie de respuesta para la optimización del proceso, dando como resultado los niveles óptimos para los factores de control temperatura y presión. De acuerdo con las pruebas, el rendimiento de la extracción del aceite se puede mantener en un 35 % de la semilla.

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“…Based on the discussions above, it could be concluded that the regression model was in agreement with the experimental data. 22 The optimal condition obtained using RSM was as follows: temperature, 141…”

Section: 23mentioning

confidence: 99%

The application of response surface methodology on the synthesis of grafted polypropylene through the solvothermal route

Zheng¹,

Zhao²,

Zeng³

et al. 2011

Adv Polym Technol

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Solvothermal synthesis is an important technology to prepare the inorganic matter. In this investigation, xylene-water-thermal reaction of polypropylene (PP), styrene (St), and maleic anhydride (MAH) under pressure was carried out to prepare grafting polymers. Infrared (IR) spectra and NMR spectra confirmed that MAH and St were successfully grafted onto the PP backbones. Through differential scanning calorimetry (DSC) and X-ray analysis,

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Maximization of bioconversion of castor oil into ricinoleic acid by response surface methodology

Cited by 34 publications

References 20 publications

Optimization of biotransformation from phytosterol to androstenedione by a mutant Mycobacterium neoaurum ZJUVN-08

Optimization of biotransformation from phytosterol to androstenedione by a mutant Mycobacterium neoaurum ZJUVN-08

Optimization of castor seed oil extraction process using response surface methodology

The application of response surface methodology on the synthesis of grafted polypropylene through the solvothermal route

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