2020
DOI: 10.1016/j.pt.2020.07.013
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Maximizing Impact: Can Interventions to Prevent Clinical Malaria Reduce Parasite Transmission?

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Cited by 14 publications
(19 citation statements)
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“…Another study ( Access-SMC-Partnership, 2020 ) also reported reduced mortality. Subsequent reviews concurred on the benefits of SMC ( Ashley and Poespoprodjo, 2020 ; Gutman et al, 2017 ; McCann et al, 2020 ), with reports of prevalence reduction by 65 % and incidence reduction by 80 % following SMC ( Greenwood, 2017 ; York, 2017 ). Extension of the age group to children up to 10 years of age was effective in reducing P. falciparum prevalence and incidence, although no difference in mortality was observed ( Ndiaye et al, 2019 ).…”
Section: Impact and Consequences Of Population-level Drug-based Interventions: Smc Mdamentioning
confidence: 86%
See 1 more Smart Citation
“…Another study ( Access-SMC-Partnership, 2020 ) also reported reduced mortality. Subsequent reviews concurred on the benefits of SMC ( Ashley and Poespoprodjo, 2020 ; Gutman et al, 2017 ; McCann et al, 2020 ), with reports of prevalence reduction by 65 % and incidence reduction by 80 % following SMC ( Greenwood, 2017 ; York, 2017 ). Extension of the age group to children up to 10 years of age was effective in reducing P. falciparum prevalence and incidence, although no difference in mortality was observed ( Ndiaye et al, 2019 ).…”
Section: Impact and Consequences Of Population-level Drug-based Interventions: Smc Mdamentioning
confidence: 86%
“…Measuring the impact of these interventions on clinical metrics like anemia or childhood mortality requires careful study designs that are powered to evaluate these outcomes ( Cohee et al, 2020 ). Interruption of malaria transmission is more complicated to evaluate ( McCann et al, 2020 ), but a desired outcome of interventions is to reduce infection and potentially disease in individuals not directly covered by the intervention. Historically, malaria transmission potential is measured by the entomological inoculation rate (EIR), the incidence of new infections, and gametocyte carriage ( Tusting et al, 2014 ).…”
Section: Drug Impact On Parasite Population Structurementioning
confidence: 99%
“…Malaria transmission stemming from asymptomatic individuals has gained attention as an increasing number of countries aims for malaria elimination rather than control. Most tools for intervention, such as bed nets, or indoor residual spraying (IRS), were developed and tested to reduce the number of clinical cases [1]. Their impact on asymptomatic infections and their transmission potential is little understood.…”
Section: Introductionmentioning
confidence: 99%
“…While the primary aim of school-based malaria control is to decrease the adverse consequences of Pf infection in students, there may also be indirect effects on transmission in the community. 32,33 Increasing evidence suggests both school-age children and persistent infections contribute significantly to malaria transmission. [34][35][36] As such, studies of school-based malaria control interventions should also measure the indirect effects on malaria transmission in the community.…”
Section: Discussionmentioning
confidence: 99%