Maximizing Organ Donation Opportunities Through Donation After Cardiac Death

Edwards, John M.; Mulvania, Patti; Robertson, Virginia; George, Gweneth; Hasz, Richard; Nathan, Howard M.; D’Alessandro, Anthony M.

doi:10.4037/ccn2006.26.2.101

Cited by 23 publications

(16 citation statements)

References 20 publications

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“…This case series demonstrates very acceptable early and intermediate results from LTx using category III DCD donor lungs, thereby confirming and extending the previous case report, anecdotes and abstracts (7–12).…”

Section: Discussionsupporting

confidence: 88%

“…We have described our Alfred approach to lung donor referral, assessment and general management elsewhere (22,23). DCD donor assessment attempted to incorporate the features of the University of Wisconsin DCD Evaluation Tool (12,13). Recipient selection is based on International Guidelines (24).…”

Section: Methodsmentioning

confidence: 99%

“…Subsequent lung preservation with Perfadex (Vitrolife, Goteborg, Sweden), lung recovery and transplantation followed standard practice (13,22,23,25). In order to avoid inadvertent cardiac stimulation, ventilation starts at 10 min after cardiac standstill (12). When participating in a DCD multiorgan recovery procedure the thoracic team assists the liver team with clamping of the thoracic aorta (19).…”

Section: Methodsmentioning

confidence: 99%

“…Steen reported the use of a single category II donor with good initial graft function, but death occurred from a nonrespiratory cause by 6 months (1). The successful use of category III donors has been reported in abstract form (7–11) and anecdote (2,12), with our group recently publishing a case report detailing the technique and definitions (13). Category IV retrieval is limited to two positive case reports (14,15).…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Early Lung Transplantation Success Utilizing Controlled Donation After Cardiac Death Donors

Snell

Levvey

Oto

et al. 2008

American Journal of Transplantation

116

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Section: Discussionsupporting

confidence: 88%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Early Lung Transplantation Success Utilizing Controlled Donation After Cardiac Death Donors

Snell

Levvey

Oto

et al. 2008

American Journal of Transplantation

116

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“…Despite the critical importance of supportive health care professionals in the DCD process, there is a paucity of empirical research investigating the antecedents for increasing support for donation after cardiac death within this important target population (20). Consequently, empirical research investigating ways to move DCD forward has the potential to reduce the organ shortage (21).…”

Section: Introductionmentioning

confidence: 99%

An Empirical Examination of the Antecedents of the Acceptance of Donation After Cardiac Death by Health Care Professionals

D’Alessandro

Peltier

Phelps

2008

American Journal of Transplantation

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Findings are reported from a US Department of Health and Human Services (DHHS) funded study to identify barriers to increasing support for donations after cardiac death by health professionals. A donations after cardiac death (DCD) acceptance model is conceptualized and tested via 806 survey responses from certified requestors, all of whom had their identities protected through Institutional Review Board (IRB) protocol. The overall model was significant and explained 35% of the variation in DCD support. Greater knowledge about DCD, greater trust in the organ procurement organization (OPO) and a belief that futility has been reached were all positively associated with DCD acceptance. Negative perceptions of DCD versus brain death, transitioning from caregiving to donation advocate, concerns about the DCD process and the idea that DCD leads to active participation in the death reduced its support. The three greatest impediments to support of DCD exist when health professionals feel they are playing an active role in killing the patient, that a state of death has not yet been reached, and that DCD has more psychological barriers than does the brain death donation process. Opportunities and strategic initiatives are discussed to overcome these barriers, including the value of communication and education initiatives and the need for well-trained requestors. The implementation of these strategic guidelines helped to increase the number of DCD donors by 225%.

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