In view of the extensive applications of the AFM nanorobot in the displacement of nanoparticles, this research has focused on the kinematics and dynamics of cylindrical nanoparticles in liquid environments. Since a manipulation process cannot be simultaneously observed while it is being performed, the use of computer modeling and simulation for performing a more precise manipulation operation has become of interest. In this paper, a model has been presented for the displacement of cylindrical nanoparticles in liquid medium. The major difference between modeling in the air medium and modeling in the liquid medium is due to the emergence of surface tension and drag forces and also the change of the adhesion coefficient of contact surfaces in liquid environments. In this article, the movement of cylindrical nanoparticles in liquid medium has been simulated threedimensionally. This simulation process has initially focused on kinematics, and the effective parameters in liquid medium have been used in the modeling. Then, the dynamic forces have been determined by means of the relevant free-body diagrams, and the changes of these dynamic forces during the manipulation process have been illustrated. Finally, different parameters that influence the process have been investigated. To validate the obtained results, first, by reducing the liquid medium parameters, the presented simulations have been compared with the results of manipulation in air, and then by reducing the effects of 3D (cylindrical) parameters, the obtained results have been compared with the existing results for the 2D (disk) model. Through the analysis of forces, the presented simulations make it possible to precisely move and displace various nanoparticles in a liquid environment.