Maximum knee extension velocity without external load is a stronger determinant of gait function than quadriceps strength in the early postoperative period following total knee arthroplasty

Abstract

Objective Quadriceps weakness is considered the primary determinant of gait function after total knee arthroplasty (TKA). However, many patients have shown a gap in improvement trends between gait function and quadriceps strength in clinical situations. Factors other than quadriceps strength in the recovery of gait function after TKA may be essential factors. Because muscle power is a more influential determinant of gait function than muscle strength, the maximum knee extension velocity without external load may be a critical parameter of gait function in patients with TKA. This study aimed to identify the importance of knee extension velocity in determining the gait function early after TKA by comparing the quadriceps strength. Methods This prospective observational study was conducted in four acute care hospitals. Patients scheduled for unilateral TKA were recruited (n = 186; age, 75.9 ± 6.6 years; 43 males and 143 females). Knee extension velocity was defined as the angular velocity of knee extension without external load as quickly as possible in a seated position. Bilateral knee function (knee extension velocity and quadriceps strength), lateral knee function (pain and range of motion), and gait function (gait speed and Timed Up and Go test (TUG)) were evaluated before and at 2 and 3 weeks after TKA. Results Both bilateral knee extension velocities and bilateral quadriceps strengths were significantly correlated with gait function. The knee extension velocity on the operation side was the strongest predictor of gait function at all time points in multiple regression analysis. Conclusion These findings identified knee extension velocity on the operation side to be a more influential determinant of gait function than impairments in quadriceps strength. Therefore, training that focuses on knee extension velocity may be recommended as part of the rehabilitation program in the early postoperative period following TKA. Trial registration UMIN Clinical Trials Registry (UMIN-CTR) UMIN000020036.

The Effects of Splayed Lipid Molecules on Lubrication by Lipid Bilayers

“…10 times of the size of the simulation box in the lateral direction. Notably, the simulations were performed at sliding velocities and a pressure relevant to the physiological conditions of synovial joints of healthy adults engaged in typical daily activities [6,29]. The results in Figure 2 demonstrate shear stress traces σ(t) that are quickly relaxing to steady-state values, which are positively correlated with the shear velocity for v ≥ 0.5 m/s, consistent with the governing principle of hydrodynamic dissipation (Figure 2a).…”

“…1 m/s), obtained by examining healthy adults, corresponding to a cartilage sliding velocity of ca. ωr femoral where r femoral is the radius (≈2 cm) of a femoral head in the knee joint [29].…”