May the variable magnetic field and pulse red light induce synergy effects in respiratory burst of neutrophils in vitro?

Photonic signals are broadly exploited in communication and sensing and they typically exhibit Poisson-like statistics. In a common scenario where the intensity of the photonic signals is low and one needs to remove a nonstationary trend of the signals for any further analysis, one faces an obstacle: due to the dependence between the mean and variance typical for a Poisson-like process, information about the trend remains in the variance even after the trend has been subtracted, possibly yielding artifactual results in further analyses. Commonly available detrending or normalizing methods cannot cope with this issue. To alleviate this issue we developed a suitable pre-processing method for the signals that originate from a Poisson-like process. In this paper, a Poisson pre-processing method for nonstationary time series with Poisson distribution is developed and tested on computer-generated model data and experimental data of chemiluminescence from human neutrophils and mung seeds. The presented method transforms a nonstationary Poisson signal into a stationary signal with a Poisson distribution while preserving the type of photocount distribution and phase-space structure of the signal. The importance of the suggested pre-processing method is shown in Fano factor and Hurst exponent analysis of both computer-generated model signals and experimental photonic signals. It is demonstrated that our pre-processing method is superior to standard detrending-based methods whenever further signal analysis is sensitive to variance of the signal.

show abstract

Effect of weak alternating magnetic fields on neutrophilic granulocytes. An analytical review

Shaev¹,

Novikov²

2023

Физика Биологии И Медицины

View full text Add to dashboard Cite

The article discusses the main achievements in recent years in studying the biological effects of weak and superweak low-frequency magnetic fields, either variable or combined with constant ones. Considered are neutrophil granulocytes activated by chemical stimulants or intact when the magnetic fields affect isolated cells, blood, and whole organisms. The methods include recording changes in ROS concentration levels (the most noticeable effect of exposure to a weak magnetic field), priming index, calcium homeostasis, proliferative activity, immune status, as well as the influence of various chemical agents on these indicators. The leading methods in this field are fluorescence spectrometry and chemiluminescence analysis. The experimental results indicate the biological effectiveness of this physical factor, the specific effect of which depends on the type of biosystem, its functional status, the environment, and the parameters of the fields themselves. The data obtained can have applied significance in magnetotherapy, immune response optimization in various diseases, acceleration of tissue regeneration and repair, and increasing the body's resistance to infections. They also can have academic significance since they help to identify the primary field acceptors and magnetic targets and their localization in the cell, study relationships with signal cascades, build models of biological signal amplification pathways, and find biologically significant frequencies and field amplitudes.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

May the variable magnetic field and pulse red light induce synergy effects in respiratory burst of neutrophils in vitro?

Cited by 3 publications

References 30 publications

9th International Fröhlich's Symposium: Electrodynamic Activity of Living Cells (Including Microtubule Coherent Modes and Cancer Cell Physics)

9th International Fröhlich's Symposium: Electrodynamic Activity of Living Cells (Including Microtubule Coherent Modes and Cancer Cell Physics)

Poisson pre-processing of nonstationary photonic signals: Signals with equality between mean and variance

Effect of weak alternating magnetic fields on neutrophilic granulocytes. An analytical review

Contact Info

Product

Resources

About