MCNP5 for proton radiography

Abstract

The developmental version of MCNP5 has recently been extended to provide for continuous-energy transport of high-energy protons. This enhancement involves the incorporation of several significant new physics models into the code. Multiple Coulomb scattering is treated with an advanced model that takes account of projectile and nuclear target form factors. In the next version, this model will provide a coupled sampling of both angular deflection and collisional energy loss, including straggling. The proton elastic scattering model is also new, based on recent theoretical work. Charged particle transport in the presence of magnetic fields is accomplished either by using transfer maps from the COSY INFINITY code (in void regions) or by using an algorithm adapted from the MARS code (in void regions or in scattering materials). Work is underway to validate and implement the latest versions of the Cascade-Exciton Model and the Los Alamos Quark-Gluon String Model, which will process inelastic nuclear interactions and generate secondary particles.

Evaluation of a novel sodium borocaptate-containing unnatural amino acid as a boron delivery agent for neutron capture therapy of the F98 rat glioma

“…D H is the physical dose of hydrogen that is caused by the elastic scattering between epithermal or fast neutrons and the hydrogen nucleus. The simulation using a general Monte Carlo N-particle transport code [13] was performed in order to correct all dose component caused by the difference of neutron spectrum between the surface and tumor site. The simulation was performed with the following assumption of the dimension of the rat head.…”

Synthesis and Evaluation of Dodecaboranethiol Containing Kojic Acid (KA-BSH) as a Novel Agent for Boron Neutron Capture Therapy

“…The rats were irradiated at a reactor power of 1 MW using the Heavy Water Neutron Irradiation Facility for 1 h. The therapeutic effect of BNCT was evaluated by the survival time of the animals. Radiation dose of BNCT experiments have been estimated using the same method as we have reported [ 11 , 29 , 30 , 31 , 32 , 33 ]. The equivalent dose for KA-BSH cannot be estimated because the CBEB for KA-BSH is unknown.2.10.…”

The Therapeutic Effects of Dodecaborate Containing Boronophenylalanine for Boron Neutron Capture Therapy in a Rat Brain Tumor Model

“…The BNCT dose was equal to the sum of the four individual physical dose components (boron, nitrogen, hydrogen, and gamma ray), which were calculated using a method that was previously used by our research group [16,17]. The differences in the neutron spectrum between the surface and the tumor site were simulated and corrected for using a general Monte Carlo N-particle transport code [22]. The simulations were performed while assuming the dimensions of the rat head as described by Futamura et al [16].…”