Mean Platelet Volume, Red Cell Distribution Width to Platelet Count Ratio, Globulin Platelet Index, and 16 Other Indirect Noninvasive Fibrosis Scores

Thandassery, Ragesh B.; Kaabi, Saad Al; Soofi, Madiha Emran; Mohiuddin, Syed Adnan; John, Anil; Mohannadi, Muneera; Ejji, Khalid Al; Yakoob, Rafie; Derbala, Moutaz; Wani, Hamidullah; Sharma, Manik; Dweik, Nazeeh Al; Butt, Mohammed T.; Kamel, Yasser Mostafa; Sultan, Khaleel; Pašić, Fuad; Singh, Rajvir

doi:10.1097/mcg.0000000000000489

Cited by 23 publications

(16 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Various parameters that were not included in the present study, such as "platelet distribution width," "globulin platelet index," and "platelet count," have been reported to have certain prognostic features [37][38][39]. These parameters were not included in the present study because the predictive powers of the hematological parameters that were included were considered to be superior.…”

Section: Resultsmentioning

confidence: 90%

Hematological predictors and clinical outcomes in cardiac surgery

et al. 2016

View full text Add to dashboard Cite

show abstract

Section: Resultsmentioning

confidence: 90%

Hematological predictors and clinical outcomes in cardiac surgery

et al. 2016

View full text Add to dashboard Cite

show abstract

“…Statistical analyses were performed using SPSS ver. 19.0 (SPSS, Chicago, IL) and MedCalc ver. 11.4.2.0 (MedCalc, Inc., Mariakerke, Belgium).…”

Section: Discussionmentioning

confidence: 99%

Evaluation and comparison of thirty noninvasive models for diagnosing liver fibrosis in chinese hepatitis B patients

Dong

Zhao

et al. 2018

Journal of Viral Hepatitis

View full text Add to dashboard Cite

The limitations of liver biopsy have led to the development of indirect noninvasive models for liver fibrosis assessment. We aimed to evaluate and compare the performance of 30 noninvasive models to predict fibrosis stage in treatment‐naïve and treated chronic hepatitis B (CHB) patients. A total of 576 Chinese treatment‐naïve CHB patients and 236 treated CHB patients who had undergone percutaneous liver biopsy were included in the analysis. Histological grading and staging was assessed by the Ishak scoring system. The diagnostic accuracies of 30 noninvasive models were assessed by area under the receiver operating characteristic curves (AUROCs). In treatment‐naïve CHB patients, the AUROCs of the 30 noninvasive models for discriminating significant fibrosis (SF) were less than 0.800, and only the AUROC of the PP score for diagnosing advanced fibrosis (AF) was more than 0.800, while the AUROCs of FIB‐4, FibroQ, HB‐F, Lok index, PHP score and PP score for predicting cirrhosis were greater than 0.800. In treated CHB patients, only the AUROCs of APRI, GUCI, King's score and Wang I for identifying cirrhosis were more than 0.800. The Spearman correlation analysis identified that only the changes in FCI and Virahep‐C model values were weakly correlated with changes in Ishak fibrosis scores before and after treatment (r = 0.206, p = 0.008; r = 0.187, p = 0.016, respectively). In conclusion, in Chinese CHB patients, the 30 existing noninvasive models were not suitable for assessing each stage of fibrosis except cirrhosis before and after antiviral therapy, especially in gauging progression and regression of liver fibrosis following therapy.

show abstract

“…Only non‐patented noninvasive models that comprised of serum markers routinely tested before liver biopsy (ie complete blood counts, coagulation tests and liver function tests) were eligible for this study. A total of 17 noninvasive models were included: AST to ALT ratio (AAR), Age‐platelet index (APind), APRI, CDS, Doha score, FCI, FI, FIB‐4, fibrosis quotient (FibroQ), globulin/platelet model (GP), GPR, Göteburg University Cirrhosis Index (GUCI), King's score, Lok index, Pohl score, Red cell distribution width to platelet ratio (RPR) and Virahep‐C model . Calculations of these models were presented in Table .…”

Section: Methodsmentioning

confidence: 99%

Validation and comparison of seventeen noninvasive models for evaluating liver fibrosis in Chinese hepatitis B patients

Dong

et al. 2018

Liver International

View full text Add to dashboard Cite

show abstract

Mean Platelet Volume, Red Cell Distribution Width to Platelet Count Ratio, Globulin Platelet Index, and 16 Other Indirect Noninvasive Fibrosis Scores

Abstract: King's score for significant and advanced fibrosis and the APRI or FIB-4 score for cirrhosis could be the best simple indirect noninvasive scores.

Cited by 23 publications

References 29 publications

Hematological predictors and clinical outcomes in cardiac surgery

Hematological predictors and clinical outcomes in cardiac surgery

Evaluation and comparison of thirty noninvasive models for diagnosing liver fibrosis in chinese hepatitis B patients

Validation and comparison of seventeen noninvasive models for evaluating liver fibrosis in Chinese hepatitis B patients

Contact Info

Product

Resources

About