Measles vaccination coverage among five‐year‐old children: implications for disease elimination in Australia

Lawrence, Glenda; MacIntyre, C. Raina; Hull, Brynley P; McIntyre, Peter

doi:10.1111/j.1467-842x.2003.tb00419.x

Cited by 12 publications

(5 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…21 A birth cohort of 64 000 children aged 5 years old in Australia also reported that the most important reason for non-uptake of measles vaccination was lack of awareness. 22 However, our study found no difference in vaccination status associated with parental awareness.…”

Section: Discussioncontrasting

confidence: 73%

Gap in measles vaccination coverage among children aged 9 months to 10 years in Ho Chi Minh City, Viet Nam, 2014

Cuong

Nguyen

Pham

et al. 2019

WPSAR

View full text Add to dashboard Cite

Introduction: When Viet Nam launched the Expanded Programme on Immunization in 1981, it covered six vaccines, including measles. Subsequently, Viet Nam experienced a marked reduction in measles infections. A nationwide measles epidemic occurred in April 2014 and an investigation found that 86% of affected children aged 9 months to 10 years were not fully vaccinated; therefore, understanding the reasons for not vaccinating could improve vaccination coverage. Method: We performed a cross-sectional study to determine vaccination coverage and reasons for non-vaccination among children aged 9 months to 10 years in six districts in Ho Chi Minh City with the highest number of measles cases in 2014. Measles vaccination status of the youngest child in each household was determined and reasons for non-vaccination were investigated. A χ2 test and multiple logistic regression were used to identify independent predictors of full vaccination. Results: In total, 207 children were enrolled during the study period in 2014. Full measles vaccination coverage was 55% in these households, and 73% of parents were aware of the importance of measles vaccination to protect their children. We found that the father’s education level (under high school versus high school and above) and the site where the survey was conducted were significantly associated with vaccination status. Conclusion: The vaccination coverage was lower than the coverage reported by district preventive medicine centres of the seven study wards. Lack of the second vaccination was a key obstacle to eliminating the vaccination gap. A catch-up mass vaccination campaign or health promotion of measles vaccination directed towards parents should be considered to improve vaccination coverage.

show abstract

Section: Discussioncontrasting

confidence: 73%

Gap in measles vaccination coverage among children aged 9 months to 10 years in Ho Chi Minh City, Viet Nam, 2014

Cuong

Nguyen

Pham

et al. 2019

WPSAR

View full text Add to dashboard Cite

show abstract

“…Just as those who perceive a threat to be severe will take action to prevent its occurrence, those who believe an intervention is harmful will avoid it. Australian research has previously demonstrated that the most common reason for parental objection to vaccination was based upon the perception that the risk outweighed the benefit 22 . The significantly greater number of MMR side effects encountered by the non‐immunisers implies that non‐immunisers perceive a genuine risk of vaccination, and not just a theoretical one.…”

Section: Discussionmentioning

confidence: 99%

Knowledge, attitudes and opinions towards measles and the MMR vaccine across two NSW cohorts

Brieger

Edwards

Mudgil

et al. 2017

Australian and New Zealand Journal of Public Health

View full text Add to dashboard Cite

Objective: Although the number of national measles cases has greatly decreased since 1980s, there has been resurgence in disease incidence in recent years. While parental knowledge and attitudes toward both disease and vaccinations are known to influence vaccine uptake, the contribution of these factors toward vaccination rates in NSW populations has not been studied. The aim of this study was to investigate the knowledge and opinions on measles and MMR vaccine in NSW Central and North Coast regions. Methods: Parents (n=201) of children <12 years were surveyed with a purpose design survey at public beaches at the Central Coast and community markets at the North Coast. Results: Eight per cent of respondents reported not immunising their child with MMR vaccine. Most respondents recognised that measles is a highly contagious disease. Non‐immunisers were found to be older, had a lower perceived severity of measles, were less likely to agree with the efficacy and safety of the vaccine, and were more likely to have encountered someone who had suffered side‐effects of the vaccine. Conclusions: There is considerable concern over safety of MMR vaccine among non‐immunisers. Implications for public health: Improving confidence in MMR vaccine should be a target of future public health interventions.

show abstract

“…Immunity results in depletion of susceptible hosts through the course of each epidemic; thereafter host replenishment requires births of susceptible individuals or loss of immunity -which is why pathogens that convey strong, long-lasting immunity result in "childhood diseases" (53). Rapid contagion, in turn, results in fast transmission among hosts, which is a shortterm evolutionary benefit to the pathogen (32,54).…”

Section: Discussionmentioning

confidence: 99%

Pertussis toxin inhibits neutrophil recruitment to delay antibody-mediated clearance of Bordetella pertussis

Kirimanjeswara¹

2005

Journal of Clinical Investigation

136

127

View full text Add to dashboard Cite

Whooping cough is considered a childhood disease, although there is growing evidence that children are infected by adult carriers. Additionally, increasing numbers of vaccinated adults are being diagnosed with Bordetella pertussis disease. Thus it is critical to understand how B. pertussis remains endemic even in highly vaccinated or immune populations. Here we used the mouse model to examine the nature of sterilizing immunity to B. pertussis. Antibodies were necessary to control infection but did not rapidly clear B. pertussis from the lungs. However, antibodies affected B. pertussis after a delay of at least a week by a mechanism that involved neutrophils and Fc receptors, suggesting that neutrophils phagocytose and clear antibody-opsonized bacteria via Fc receptors. B. pertussis blocked migration of neutrophils and inhibited their recruitment to the lungs during the first week of infection by a pertussis toxin-dependent (PTx-dependent) mechanism; a PTx mutant of B. pertussis induced rapid neutrophil recruitment and was rapidly cleared from the lungs by adoptively transferred antibodies. Depletion of neutrophils abrogated the defects of the PTx mutant. Together these results indicate that PTx inhibits neutrophil recruitment, which consequently allows B. pertussis to avoid rapid antibody-mediated clearance and therefore successfully infect immune hosts.

show abstract

Measles vaccination coverage among five‐year‐old children: implications for disease elimination in Australia

Cited by 12 publications

References 9 publications

Gap in measles vaccination coverage among children aged 9 months to 10 years in Ho Chi Minh City, Viet Nam, 2014

Gap in measles vaccination coverage among children aged 9 months to 10 years in Ho Chi Minh City, Viet Nam, 2014

Knowledge, attitudes and opinions towards measles and the MMR vaccine across two NSW cohorts

Pertussis toxin inhibits neutrophil recruitment to delay antibody-mediated clearance of Bordetella pertussis

Contact Info

Product

Resources

About