Measurement of ataxic symptoms with a graphic tablet: standard values in controls and validity in Multiple Sclerosis patients

Erasmus, Lutz-Peter; Sarno, Stefania; Albrecht, H.; Schwecht, Martina; Pöllmann, W.; König, N.

doi:10.1016/s0165-0270(01)00373-9

Cited by 78 publications

(54 citation statements)

References 24 publications

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“…Therefore, only healthy controls performed the digitised spiral drawing bilaterally. As in other drawing research (Erasmus et al, 2001), no significant differences between the dominant and non-dominant hand performance were found, indicating that hand dominance does not influence the voluntary spiral drawing movements. Hand dominance may, however, have affected the execution times of the TEMPA items, but cannot play a role in different correlation coefficients found between circle and square drawing, and the clinical assessment.…”

Section: The Influence Of Hand Dominancesupporting

confidence: 65%

“…One study in patients with MS reported the quantification of ataxic symptoms including intention tremor based on figure '8' drawings on a digitising tablet (Erasmus et al, 2001). Studies in essential tremor and Parkinson's disease have reported the use of digitised spiral drawing for quantifying tremor (Elble et al, 1996;Pullman, 1998;Louis et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

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Digitised spirography as an evaluation tool for intention tremor in multiple sclerosis

Feys

Helsen

Prinsmel

et al. 2007

Journal of Neuroscience Methods

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Section: The Influence Of Hand Dominancesupporting

confidence: 65%

Section: Introductionmentioning

confidence: 99%

Digitised spirography as an evaluation tool for intention tremor in multiple sclerosis

Feys

Helsen

Prinsmel

et al. 2007

Journal of Neuroscience Methods

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“…The execution time reflects manual dexterity, which is influenced by tremor severity. The time limit was 300 s [27]. An Activities of Daily Living (ADL) questionnaire consisted of 25 questions concerning activities of daily life.…”

Section: Clinical Assessmentmentioning

confidence: 99%

The effect of levetiracetam on tremor severity and functionality in patients with multiple sclerosis

et al. 2009

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“…Digitising tablets can be used to quantify normal (Lacquaniti et al, 1987;Mergl et al, 1999) and tremulous arm movements (Elble et al, 1996;Erasmus et al, 2001;Pullman, 1998). Spiral drawing may be particularly suited to quantifying involuntary arm movements involving more than just a single joint, as in order to draw a spiral in 2D both the distal and proximal arm joints must be used.…”

Section: Introductionmentioning

confidence: 99%

Quantifying drug-induced dyskinesias in the arms using digitised spiral-drawing tasks

Liu

Carroll

Wang

et al. 2005

Journal of Neuroscience Methods

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In this study, we quantify the severity of drug-induced dyskinesias in the arms of Parkinson's disease (PD) patients using digitised spiral-drawing tasks. Two spiral drawings, namely a circular and a square spiral, are designed to, respectively, represent the continuous and discrete arm motions, and the size of the spiral is decided so that both the distal and proximal arm joints are involved. Fifteen PD patients, average disease duration 14.4+/-7.4 years, were assessed 30 min after a levodopa challenge whilst performing circular and square spiral-drawing tasks. The velocity of drawing movements was computed and the amplitude of the involuntary dyskinetic movements was measured as the standard deviation of the drawing velocity (SD-DV). The mean amplitude of dyskinetic movements was compared between arms and tasks and was correlated with clinical measures including the Bain dyskinesia scale and the total unified Parkinson's disease rating scale (UPDRS) score. The results showed that there was no statistically significant difference in the amplitude of dyskinesias either between the arms or between the continuous (circular) and discrete (square) spiral drawings in this group of PD patients, but interestingly the interaction between arm and drawing pattern was significant. Significant correlations were found between the magnitude of dyskinesia measured from the spiral-drawing tasks and both the 'on' or 'off' UPDRS and also the Bain dyskinesia scale. We conclude that the drawing tasks may be used to provide an objective method of quantifying the severity of drug-induced dyskinesias in the arm in PD patients.

show abstract

Measurement of ataxic symptoms with a graphic tablet: standard values in controls and validity in Multiple Sclerosis patients

Cited by 78 publications

References 24 publications

Digitised spirography as an evaluation tool for intention tremor in multiple sclerosis

Digitised spirography as an evaluation tool for intention tremor in multiple sclerosis

The effect of levetiracetam on tremor severity and functionality in patients with multiple sclerosis

Quantifying drug-induced dyskinesias in the arms using digitised spiral-drawing tasks

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