Measurement of Bovine Bone Properties through Surface Indentation Technique

Abstract

The mechanical and micro-structural properties of cortical bovine bone have been extensively studied due to the fact that its micro-structural components would significantly reflect the global mechanical behavior of the bone. The objective of this paper is to study the elastic modulus and hardness of a bovine cortical bone, in both longitudinal and transverse directions by using nano-indentation technique. The moduli in the longitudinal and transverse directions were recorded as 16.23 GPa and 10.26 GPa, respectively. While the hardness readings in the longitudinal and transverse directions were 0.505 GPa and 0.387 GPa, respectively.According to the result shown, it is suggested that heterogeneous properties of the bone is assumed and the measurements of their properties are highly dependent on tissue types, anatomical location and bone mineral content distribution.

Collagen fibril organization within rat vertebral bone modified with metastatic involvement

“…This is supported by findings that microstructural changes in collagen fibril arrangement accounted for the maintenance of bone strength despite reduced mineral density in bone subjected to prolonged physical activity (Puustjarvi et al, 1999), and the relationship between orientation dependent fracture energy and collagen orientation in bone (Peterlik et al, 2006). Tissue-level assessed mechanical properties of bone tissue such as modulus and hardness have been shown to be impacted by differences in relative collagen orientation (Zysset et al, 1999;Lau et al, 2010). The nanostructural level describes the morphological and structural characteristics of a single fibril; and interactions between the neighbouring fibrils.…”

Elevated Microdamage Spatially Correlates with Stress in Metastatic Vertebrae

“…BSE image analysis also revealed quantitative differences in load induced microdamage in metastatic vs. healthy vertebral bone as indicated by greater relative increases in FWHM and GLMax between loaded and unloaded specimens. Bone plasticity and deformation are associated with features of the tissue matrix such as the orientation of collagen fibrils 64,29 intrafibrillar collagen cross-linking 47 , as well as fibril-fibril and fibril-mineral interactions 62,30 .…”

Biomechanical Properties of Metastatically Involved Osteolytic Bone

“…The rectilinear array of collagen-I fibrils has been shown to contribute to the toughness of bone [14][15][16]. Collagen organization has also been shown to affect modulus and hardness [17,18]. Osteolytic metastatic involvement has been shown to impact collagen organization in both trabecular and cortical bone, with increased collagen fibril disorganization associated with reduced hardness and modulus [19][20][21][22].…”