A B S T R A C T Placental transport of vitamin Bn was studied in the pregnant rat in two series of experiments. In the first series animals were given cyanocobalamin-'7Co intravenously at various stages of gestation. High specific activity tracer was used and doses of Bn were 1-2 ng per animal. The rats were killed from 15 min to 24 hr after injection and the fetuses, placentas, and serum were assayed for radioactivity. In the second series using uninjected animals, absolute amounts of vita-