Measurement of creatine kinase isoforms by agarose gel electrophoresis in the diagnosis of myocardial infarction

Shiesh, Shu Chu; Ting, Wen-Kao; Jap, Tjin-Shing

doi:10.1016/0009-9120(92)80036-g

Cited by 5 publications

(1 citation statement)

References 24 publications

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“…Agarose-based hydrogels have considerably been utilized in the investigation of mechanical load reaction for chondrocytes and mesenchymal stem cells (MSCs) [22]. Agarose has acquired a wide range of applications such as drug delivery [23,24], cancer therapy [25,26], tissue engineering and regenerative medicine [27][28][29][30], and disease diagnosis, controlling, and treatment [31][32][33]. It has been utilized in various tissue engineering applications, including the neural system [34], bone formation [35], cardiac regeneration, wound healing, and attachment to tissues such as skin [36], brain [37], and cornea.…”

Section: Introductionmentioning

confidence: 99%

Agarose-Based Biomaterials: Opportunities and Challenges in Cartilage Tissue Engineering

et al. 2020

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The lack of adequate blood/lymphatic vessels as well as low-potential articular cartilage regeneration underlines the necessity to search for alternative biomaterials. Owing to their unique features, such as reversible thermogelling behavior and tissue-like mechanical behavior, agarose-based biomaterials have played a key role in cartilage tissue repair. Accordingly, the need for fabricating novel highly efficient injectable agarose-based biomaterials as hydrogels for restoration of injured cartilage tissue has been recognized. In this review, the resources and conspicuous properties of the agarose-based biomaterials were reviewed. First, different types of signals together with their functionalities in the maintenance of cartilage homeostasis were explained. Then, various cellular signaling pathways and their significant role in cartilage tissue engineering were overviewed. Next, the molecular structure and its gelling behavior have been discussed. Eventually, the latest advancements, the lingering challenges, and future ahead of agarose derivatives from the cartilage regeneration perspective have been discussed.

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Section: Introductionmentioning

confidence: 99%

Agarose-Based Biomaterials: Opportunities and Challenges in Cartilage Tissue Engineering

et al. 2020

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Noninvasive assessment of reperfusion and reocclusion after thrombolysis in acute myocardial infarction

Klootwijk¹,

Cobbaert²,

Fioretti³

et al. 1993

The American Journal of Cardiology

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The clinical significance of ST-segment changes and of the time course of appearance in serum of different cardiac proteins has been reviewed for the diagnosis of coronary reperfusion and reocclusion after thrombolysis. In particular, the value of serial 12-lead electrocardiographic (ECG) studies, of Holter monitoring, and of continuous multilead computer-assisted ECG monitoring is compared. Regarding the serum proteins, the clinical significance of reperfusion indices described so far for serum creatine kinase (CK), its isoenzyme serum creatinine kinase MB, the CK isoforms, and myoglobin is reviewed. Emphasis is placed on (1) the calculation method used for deriving the reperfusion indices; (2) the sensitivity and the specificity of the reperfusion indices; (3) the minimum turn-around time needed to produce the reperfusion indices (depending on the practicability of the analytical and calculation methods and their applicability in an emergency laboratory); (4) the ability of the indices to produce reliable estimates of reperfusion efficacy of the thrombolytic agents under study; and (5) the ability of the marker proteins to detect reinfarction as well as the suitability of the markers to detect real-time necrosis.

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The sum of vectors method (SV) applied to lactate dehydrogenase isoenzymes and creatine kinase isoforms

Šalplachta

1997

Clinica Chimica Acta

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Measurement of creatine kinase isoforms by agarose gel electrophoresis in the diagnosis of myocardial infarction

Cited by 5 publications

References 24 publications

Agarose-Based Biomaterials: Opportunities and Challenges in Cartilage Tissue Engineering

Agarose-Based Biomaterials: Opportunities and Challenges in Cartilage Tissue Engineering

Noninvasive assessment of reperfusion and reocclusion after thrombolysis in acute myocardial infarction

The sum of vectors method (SV) applied to lactate dehydrogenase isoenzymes and creatine kinase isoforms

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