Measurement of Jugular Venous Blood Gases for Prediction of Brain Ischaemia Following Carotid Ligation

Jawad, Khalil; Miller, J. D.; Fitch, W.; Barker, J.

doi:10.1159/000114725

Cited by 9 publications

(2 citation statements)

References 11 publications

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“…Cerebral blood flow was measured by the clearance of 133Xenon from the brain as described in our previous publications (Wyper and Rowan, 1973;Leech et al, 1974;Jawad et al, 1976;Jawad et al, 1977). Details of measurement of other physiological variables (systemic and internal carotid arterial pressure, arterial blood gases, end-tidal C02, and body temperature and EEG) have also been reported previously .…”

Section: Intraoperative Measurementsmentioning

confidence: 99%

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Safety of carotid ligation and its role in the management of intracranial aneurysms.

Miller¹,

Jawad²,

Jennett³

1977

Journal of Neurology, Neurosurgery & Psychiatry

153

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From the MRC Group for the Study of the Cerebral Circulation, Institute of Neurological Sciences, Glasgow S U MM AR RY By using measurements of cerebral blood flow and internal carotid artery pressure it is possible to select patients in whom carotid ligation can be performed with a very low risk of postoperative cerebral ischaemia. A study has been carried out in 100 patients comparing this method with clinical predictions of the type used in aneurysm surgery based on age of the patient, arterial hypertension, time from latest subarachnoid haemorrhage, and neurological status on a modified Botterell scale. These clinical factors were found to be of little value in predicting which patients would and would not develop cerebral ischaemia after carotid occlusion.

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Section: Intraoperative Measurementsmentioning

confidence: 99%

“…Measurements of several parameters derived from ipsilateral jugular venous blood samples were compared with CBF measurements and proved to be without value in indicating even severe hemisphere ischaemia (Jawad et al, 1976).…”

mentioning

confidence: 99%

Safety of carotid ligation and its role in the management of intracranial aneurysms.

Miller¹,

Jawad²,

Jennett³

1977

Journal of Neurology, Neurosurgery & Psychiatry

153

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show abstract

Physiological responses to focal cerebral ischemia in humans

Powers¹,

Grubb²,

Raichle³

1984

Annals of Neurology

248

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Positron emission tomography (PET) was used to investigate the regional hemodynamic and metabolic changes that accompany focal reductions in cerebral blood flow to ischemic but uninfarcted regions of the brain. Studies were performed on 7 patients chosen from a larger group of subjects with transient ischemic attacks and normal computed tomographic findings, specifically because their PET studies showed decreased blood flow to the symptomatic hemisphere rather than symmetrical flow to the two hemispheres. In regions with decreased blood flow, the cerebral metabolic rate for oxygen was also decreased, but to a lesser degree. Cerebral blood volume, vascular mean transit time, and fractional extraction of oxygen from blood were all increased. These findings indicate that cerebral oxygen metabolism was maintained in the face of decreased blood flow by local compensatory mechanisms that included dilation of intraparenchymal blood vessels and increased transfer of oxygen from blood to tissue. Such knowledge of the physiological characteristics of ischemic, uninfarcted brain is important if PET is to be used clinically to differentiate reversible cerebral ischemia from irreversible infarction.

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Jugular Venous Bulb Oxygen Saturation and Cerebral Blood Flow Measurement in Intensive Care

Garlick¹

1988

Current Concepts in Critical Care

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Measurement of Jugular Venous Blood Gases for Prediction of Brain Ischaemia Following Carotid Ligation

Cited by 9 publications

References 11 publications

Safety of carotid ligation and its role in the management of intracranial aneurysms.

Safety of carotid ligation and its role in the management of intracranial aneurysms.

Physiological responses to focal cerebral ischemia in humans

Jugular Venous Bulb Oxygen Saturation and Cerebral Blood Flow Measurement in Intensive Care

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