1973
DOI: 10.1159/000240580
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Measurement of Liver Blood Flow in the Infant Monkey

Abstract: Liver blood flow in infant monkeys (M speciosa) was measured with both the fractional clearance flow rate technique and the microsphere technique in an attempt to evaluate these methods comparatively and to quantitate liver blood flow in the newborn nonhuman primate. Cardiac output, blood volume and regional hepatic arterial, splenic, gastrointestinal, pancreatic and mesenteric blood flows were determined. With the fractional clearance technique mean liver sinusoidal blood flow was 35.2 ml/min or 1.48 ml/min/g… Show more

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Cited by 7 publications
(5 citation statements)
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“…Among these clearance techniques are commonly used [14,20,25]. They have been compared with each other [26,29], with the oldest method of collecting the outflow [15], and with the electromagnetic methods [25] and have been demonstrated to be nearly as reliable.…”
Section: Discussionmentioning
confidence: 99%
“…Among these clearance techniques are commonly used [14,20,25]. They have been compared with each other [26,29], with the oldest method of collecting the outflow [15], and with the electromagnetic methods [25] and have been demonstrated to be nearly as reliable.…”
Section: Discussionmentioning
confidence: 99%
“…Oxygen content was measured with a Lcx-0;-Con and total C 03 was calculated from the Siggaard-Andersen nomo gram (16) Arterial plasma samples were analyzed for insulin by double antibody radioimmunoassay (17) and glucagon using Unger antiserum 30K (18). Car diac output and hindlimb blood flows were computed using radioactive microsphere injection and timed withdrawal of an arterial blood sample (19). These were used to quantitate substrate, oxygen, and carbon dioxide flux.…”
Section: Methodsmentioning
confidence: 99%
“…developed nomogram (22). Using a radioactive microsphere technique (21), cardiac output and cerebral cortex blood flows were determined in five neonates in the first 48 hr of life and in two infants at 6 and 12 weeks, respectively. These were used to compute cerebral glucose and oxygen consumption.…”
Section: Methodsmentioning
confidence: 99%