Measurement of pulsatile flow using MRI and a Bayesian technique of probability analysis

Wise, Richard G.; Newling, Benedict; Gates, A. R. C.; Xing, Da; Carpenter, T. Adrian; Hall, Laurance D.

doi:10.1016/0730-725x(95)02059-3

Cited by 13 publications

(6 citation statements)

References 29 publications

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“…The use of two points in q ‐space to measure velocity constitutes a phase subtraction technique (35). The use of more q ‐samples increases imaging time proportionately, but also increases the signal‐to‐noise ratio (SNR) of the resulting velocity maps (30, 31).…”

Section: Methodsmentioning

confidence: 99%

“…The present study extends the MRI approach to a detailed determination of flow patterns and cardiac wall motion within the heart and aorta during systole and diastole in anesthetized Wistar Kyoto (WKY) rats. It employs recently developed data‐processing and motion‐encoding acquisition strategies (30, 31) to improve velocity measurement using a PC technique combined with a gradient‐echo cine imaging sequence. Our analysis establishes the direction and magnitude of blood flow in three spatial dimensions, as well as its variation with time through the cardiac cycle, and provides a basic description of the cardiac flow patterns in multiple image planes covering the heart.…”

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confidence: 99%

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Simultaneous measurement of blood and myocardial velocity in the rat heart by phase contrast MRI using sparse q‐space sampling

Wise

Al-Shafei

Carpenter

et al. 2005

Magnetic Resonance Imaging

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Purpose: To measure cardiac blood flow patterns and ventricular wall velocities through the cardiac cycle in anesthetized Wistar Kyoto (WKY) rats. Materials and Methods:A gradient-echo cine pulse sequence incorporating pulsed field gradients (PFGs) provided phase contrast (PC) motion encoding. We achieved a range of velocity sensitivity that was sufficient to measure simultaneously the large flow velocities within the cardiac chambers and aortic outflow tract (up to 70 cm s -1 during systole), and the comparatively small velocities of the cardiac wall (0 -3 cm s -1 ). A scheme of sparsely sampling q-space combined with a probability-based method of velocity calculation permitted such measurements along three orthogonal axes, and yielded velocity vector maps in all four chambers of the heart and the aorta, in both longitudinal and transverse sections, for up to 12 time-points in the cardiac cycle.Results: Left ventricular systole was associated with a symmetrical laminar flow pattern along the cardiac axis, with no appearance of turbulence. In contrast, blood showed a swirling motion within the right ventricle (RV) in the region of the pulmonary outflow tract. During left ventricular diastole a plume of blood entered the left ventricle (LV) from the left atrium. The ventricular flow patterns could also be correlated with measurements of left ventricular wall motion. The greatest velocities of the ventricular walls occurred in the transverse cardiac plane and were maximal during diastolic refilling. The cardiac wall motion in the longitudinal axis demonstrated a caudal-apical movement that may also contribute to diastolic refilling. Conclusion:The successful measurements of blood and myocardial velocity during normal myocardial function may be extended to quantify pathological cardiac changes in animal models of human cardiac disease.

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Section: Methodsmentioning

confidence: 99%

mentioning

confidence: 99%

Simultaneous measurement of blood and myocardial velocity in the rat heart by phase contrast MRI using sparse q‐space sampling

Wise

Al-Shafei

Carpenter

et al. 2005

Magnetic Resonance Imaging

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“…Bayesian analysis has previously been used in a variety of MR applications [7][8][9][10]. It has been shown to improve the recovery of an MR spectrum from noisy data [7] and to improve the accuracy of flow measurements by enabling a sparse sampling procedure to be used [9].…”

Section: Introductionmentioning

confidence: 99%

A Bayesian approach to characterising multi-phase flows using magnetic resonance: Application to bubble flows

Holland

Blake

Tayler

et al. 2011

Journal of Magnetic Resonance

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“…Bayesian analysis has previously been used to reconstruct spectral data in NMR [19][20][21], estimate velocity and diffusion during pulsatile flow [21], and to obtain measurements of bubble size distributions in gas-liquid flows [22]. In the Bayesian approach to data analysis, we seek to identify a particular parameter of interest, and do not necessarily require the reconstruction of an entire image.…”

Section: Introductionmentioning

confidence: 99%

Extending the use of Earth’s Field NMR using Bayesian methodology: Application to particle sizing

Ross

Holland

Blake

et al. 2012

Journal of Magnetic Resonance

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Measurement of pulsatile flow using MRI and a Bayesian technique of probability analysis

Cited by 13 publications

References 29 publications

Simultaneous measurement of blood and myocardial velocity in the rat heart by phase contrast MRI using sparse q‐space sampling

Simultaneous measurement of blood and myocardial velocity in the rat heart by phase contrast MRI using sparse q‐space sampling

A Bayesian approach to characterising multi-phase flows using magnetic resonance: Application to bubble flows

Extending the use of Earth’s Field NMR using Bayesian methodology: Application to particle sizing

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