Measurement of serum thyroxine binding prealbumin in various thyroidal states by radioimmunoassay.

Ishida, Masao; Kajita, Yoshihiro; Ochi, Yukio; Hachiya, Takashi; Miyazaki, Tadayoshi; Yoshimura, Manabu; Ijichi, Hamao

doi:10.1507/endocrj1954.29.607

Cited by 8 publications

(2 citation statements)

References 23 publications

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“…Figure 1 supports the claim that the thyroxine availability index reflects thyroid status (figs, la, Id) and can be used in monitoring the efficacy of thyroid treatment (figs, le, If). Similar findings have been described by Ishida et al (27), who noticed that transthyretin levels did not return to normal in treated hypo-and hyperthyroid patients until a euthyroid state was attained.…”

Section: Discussionsupporting

confidence: 90%

Transthyretin – An Explanation of “Anomalous” Serum Thyroid Hormone Values in Severe Illness?

Ramaker

Wood²

1990

Clinical Chemistry and Laboratory Medicine

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Section: Discussionsupporting

confidence: 90%

Transthyretin – An Explanation of “Anomalous” Serum Thyroid Hormone Values in Severe Illness?

Ramaker

Wood²

1990

Clinical Chemistry and Laboratory Medicine

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“…Low concentrations of TTR were found by Vergani et al [78] in patients with untreated thyrotoxicosis, but the values recorded in the majority of cases with untreated hypothyroidism were within normal range. The concentrations of transthyretin were measured also by Ishida et al [79] in patients with various thyroidal states. In patients with untreated hyperthyroidism, markedly low serum TTR values were found, but were normalized by treating with anti-thyroid drug.…”

Section: Disease Markermentioning

confidence: 99%

Transthyretin in the Evaluation of Health and Disease in Human and Veterinary Medicine

Tóthová¹,

Nagy²

2018

Pathophysiology - Altered Physiological States

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Transthyretin (also known as prealbumin) is an important transport protein, which plays an essential role in the binding of thyroid hormones and retinol with varying affinities in mammalian, as well as avian species. The determination of transthyretin concentrations may be used as a diagnostic tool for some disease conditions in humans, but is more often used as a nutritional marker to assess protein-calorie malnutrition and as prognostic indicator in critically ill patients. Transthyretin has shorter half-life (2-3 days) than that of albumin and belongs to negative acute phase proteins. This may complicate the use of transthyretin as a nutritional marker and the interpretation of results in the diagnosis of diseases. Although some studies have been carried out to determine the usefulness of transthyretin in selected disease conditions and disorders also in animals, it is a relatively rarely used parameter to evaluate health state and illness in veterinary medicine. The usefulness of transthyretin in the diagnosis of diseases and evaluation of nutritional status in humans and animals are reviewed in this article, including the laboratory assays available to measure its concentrations and the possible clinical application of the results, as well as its usefulness as a prognostic indicator in some disease conditions.

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Transthyretin and the Transthyretin Amyloidoses

Buxbaum

Protein Misfolding, Aggregation, and Conformational Diseases

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Measurement of serum thyroxine binding prealbumin in various thyroidal states by radioimmunoassay.

Cited by 8 publications

References 23 publications

Transthyretin – An Explanation of “Anomalous” Serum Thyroid Hormone Values in Severe Illness?

Transthyretin – An Explanation of “Anomalous” Serum Thyroid Hormone Values in Severe Illness?

Transthyretin in the Evaluation of Health and Disease in Human and Veterinary Medicine

Transthyretin and the Transthyretin Amyloidoses

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