2004
DOI: 10.1191/0267659104pf755oa
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Measurement of the activated clotting time during cardiopulmonary bypass: differences between Hemotec® ACT and Hemochron® Jr apparatus

Abstract: The ACT is not a standardized measure. Test results are strongly associated with the specific compounds used to initiate the coagulation process.

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Cited by 16 publications
(21 citation statements)
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“…11 The correlation between the 2 devices was 0.526 in this study. Therefore, different brands of ACT instrumentation cannot be used interchangeably.…”
Section: Comparison Of Different Act Devicessupporting
confidence: 60%
“…11 The correlation between the 2 devices was 0.526 in this study. Therefore, different brands of ACT instrumentation cannot be used interchangeably.…”
Section: Comparison Of Different Act Devicessupporting
confidence: 60%
“…Disturbances of coagulation arise due to factors such as hemostatic system immaturity, hemodilution, systemic inflammation, prolonged bypass time, and the use of deep hypothermic circulatory arrest as well as age-related differences in responses to heparin (9). Children with congenital heart disease, particularly cyanotic polycythemic children, have further derangements of both platelet function and coagulation proteins (6,(32)(33)(34)(35)(36)(37). The physiological impact of CPB during infant surgery exceeds that in adults.…”
Section: Discussionmentioning
confidence: 99%
“…In the early 90's variability between the different systems was noted, i.e. ACT analyzers differ by activators, detection systems, and use different sample volumes [33][34][35]. Consequently, the ACT value differs for each analyzer, suggesting that extrapolation between different systems would not be appropriate [36].…”
Section: Clotting-time Based Methodsmentioning
confidence: 99%