Measurement of Thickness and Refractive Index of Optical Samples Simultaneously Using Full-Range One-Shot Frequency-Domain Optical Coherence Tomography

Cheng, Hsu-Chih; Huang, Chia-Tsai

doi:10.1080/01468030.2015.1044678

Cited by 2 publications

(2 citation statements)

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“…This proposed FD-OCT design [11] could produce one-shot images by using a fixed apochromatic quarter-wave retarder rather than a rotating polarizer and a mechanical scan. Furthermore, in our previous study, we used one-shot full-range FD-OCT that had a noise elimination feature to measure the thickness and refractive index of samples [12]. The proposed method in [12] provided full-range and one-shot measurements with twice the maximal depth position.…”

Section: Introductionmentioning

confidence: 99%

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Applying a Pix2Pix Generative Adversarial Network to a Fourier-Domain Optical Coherence Tomography System for Artifact Elimination

2021

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The presence of artifacts, including conjugate, DC, and auto-correlation artifacts, is a critical limitation of Fourier-domain optical coherence tomography (FD-OCT). Many methods have been proposed to resolve this problem to obtain high-quality images. Furthermore, the development of deep learning has resulted in many prospective advancements in the medical field; image-to-image translation by using generative adversarial networks (GANs) is one such advancement. In this study, we propose applying the Pix2Pix GAN to eliminate artifacts from FD-OCT images. The first experiment results showed that the proposed framework could translate conventional FD-OCT depth profiles into artifact-free FD-OCT depth profiles. In addition, the FD-OCT depth profile and optical distance of translated images matched those of ground truth images. Second experiment verified that the proposed GAN-based FD-OCT can be applied to generate artifact-free FD-OCT image with different parameters of sample refractive index, the front surface of the sample toward the zero-delay position, and the physical thickness of the sample. Third experiment proved that the proposed model could translated the conventional FD-OCT depth profiles with additional Gaussian noises source image into artifacts-free FD-OCT and successfully relieved the noise.INDEX TERMS Artifacts, FD-OCT, image-to-image translation, Pix2Pix GAN the FD-OCT system is more sensitive around the zero-delay line, imaging is performed by positioning the zero-delay line at the region of interest in a sample to obtain double-depth range images. Sanjay et al.[1] used spectral-domain OCT (SD-OCT) to examine patients diagnosed as having glaucoma and reported that 15.2%-36% of scans showed artifacts that may cause difficulty to physicians in the analysis of images. A study identified various types of artifacts that can lead to an incorrect diagnosis [2]. Because artifacts can obscure imaging results and prevent the detection of critical features in a sample structure, full-range FD-OCT is commonly implemented using phase shifting to reconstruct the sample structure and overcome this complex artifact problem. Full-range FD-OCT images are obtained by recording several interferograms with different phase relations. Jiewen et al. [3] proposed a five-frame variable phase-shifting (FVP) method to reduce the effects of polychromatic errors. Compared with the traditional five-

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Section: Introductionmentioning

confidence: 99%

“…Furthermore, in our previous study, we used one-shot full-range FD-OCT that had a noise elimination feature to measure the thickness and refractive index of samples [12]. The proposed method in [12] provided full-range and one-shot measurements with twice the maximal depth position.…”

Section: Introductionmentioning

confidence: 99%