Measurement of total body potassium with a shadow
shield whole-body counter: calibration and errors

Boddy, K.; King, Priscilla C.; Tothill, P.; Strong, Judith A.

doi:10.1088/0031-9155/16/2/310

Cited by 71 publications

(35 citation statements)

References 9 publications

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“…This measurement was the mean of two readings using the Merlin mobile whole-body radioactivity monitor (Boddy, 1967). The readings obtained were expressed as Eq of K by using a calibration equation derived by Boddy, King, Tothill & Strong (1971). The mean values were 3.730 Eq (3-13W450) for the men and 2.420 Eq (2.060-24310) for the women.…”

Section: Methodr Of Estimating Ffmmentioning

confidence: 99%

A Comparison of the Fat-Free Mass of Young Adults Estimated by Anthropometry, Body Density and Total Body Potassium Content

et al. 1972

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S U M M A R Y1. The fat-free mass (FFM) of ten male and ten female subjects was calculated from measurement of (i) height and weight, (ii) skinfold thickness, (iii) body density, (iv and v) total body potassium by two different methods. All the subjects were apparently healthy and in the medium range of body build and they were mainly young adults.2. The mean FFM of the ten male subjects was similar as calculated by all methods, although comparisons between pairs of methods sometimes produced discrepancies of up to 2 kg.3. Agreement was less good for the females but, with the exception of one of the potassium methods, still reasonable. 4. The potassium content of the FFM as mEq K/kg of FFM, was compared with the direct analysis of Forbes, Gallup & Hursh (1961) on four male cadavers. The agreement was close for the men but the K content of the FFM in women was lower than that for men. This difference is discussed.Key words : fat-free mass, anthropometry, body density, total body potassium content.The assessment of the amount of body fat in individual men and women is now a relatively common procedure. When the fat content of the body is known, the fat-free mass (FFM) may also be determined by simple arithmetical subtraction from the total body weight. Both of these quantities, fat and the FFM, reflect nutritional status and are of considerable medical and physiological interest. The assesssment of obesity and the regulation of desirable weight loss may also require a knowledge of the fat and FFM of the body.Several techniques are now used to estimate body fat and the FFM. These depend usually on extrapolations from measurements (i) by anthropometry of height, weight, skinfold thickness and girths, (ii) of total body water, (iii) of the density of the body, and (iv) of total body potassium. The present paper compares the results of measuring the FFM by five different methods using some of these techniques.Correspondence: Dr J. Womersley, Institute of Physiology, The University, Glasgow G12 8QQ. 469. 470 J. Womersley et al. M E T H O D STen men and ten women, all apparently healthy, acted as subjects; the mean values (and ranges) for age, height and weight were: men, 24 years (17-30), 179 cm (163-191), 68.0 kg (57.0-81.2); women, 28 years (16-54), 160 cm (152-170), 57.0 kg (44.4-68.3). Methodr of estimating FFM Height and weight. Hume & Weyers (1971) measured total body water (TBW) by tritium dilution, and the height and weight, of thirty men and thirty women aged between 33 and 84 years. They established the following regression equations. Men: TBW (litres)=0.297 Wt. (kg) + 0.195 height (cm)-14.013 Women: TBW (litres)=0.184 Wt. (kg) + 0.345 height (em) -35.270We have calculated the FFM of our subjects from measurements of height and weight by using these regressions and the relationship (FFM = 100 TBW/73) established by Rathbun & Pace (1945).Skinfold thickness. Measurement of skinfold thickness was made at four sites on both sides of the body : over the biceps and triceps muscles and at the subscapular and supraili...

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Section: Methodr Of Estimating Ffmmentioning

confidence: 99%

A Comparison of the Fat-Free Mass of Young Adults Estimated by Anthropometry, Body Density and Total Body Potassium Content

et al. 1972

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“…The measured values were corrected for changes in sensitivity of the scanner and any change in body size of the patient between measurements using a correction factor previously described (Boddy et al, 1971). Coefficient of variation of measurement was 2%.…”

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Energy balance in patients with advanced NSCLC, metastatic melanoma and metastatic breast cancer receiving chemotherapy – a longitudinal study

et al. 2005

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Chemotherapy exerts a variable effect on nutritional status. It is not known whether loss of body fat or fat-free mass (FFM) during chemotherapy relates to diminished dietary intake, failure to meet elevated energy requirements, or to the presence of an acutephase response. We sought to determine prospective measurements of body mass and composition, resting energy expenditure, energy and protein intake, and C-reactive protein over a course of chemotherapy in 82 patients with advanced cancer. There was a large dropout from the study. Prospective measurements were obtained in 19 patients with non-small-cell lung cancer (NSCLC), 12 with metastatic melanoma and 10 with metastatic breast cancer. There were significant increases in energy intake among patients with metastatic breast cancer, 873 (266 -1480) kJ (mean 95% CI; Po0.01), and metastatic melanoma, 2513 (523 -4503) kJ (Po0.01). Breast cancer patients gained percentage body fat over the course of treatment, 2.1 (0.8 -3.5%). Gain or loss of body fat correlated to mean energy intake throughout chemotherapy in patients with NSCLC (Rs ¼ 0.751; Po0.01) and metastatic breast cancer (Rs ¼ 0.617; Po0.05). The ability to meet or exceed energy requirements led to gains in body fat among patients with metastatic breast cancer and NSCLC, but did not prevent loss of FFM in these groups.

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“…14 -" Total exchangeable sodium (NaE) 18 and potassium (KE), 18 together with total body sodium (TBNa) 19 and total body potassium (TBK) 20 were estimated; the coefficients of variation for duplicate estimations in the same person were 1.8%, 1.9%, 4.2%, and 3.1% respectively. Detailed findings, and the effects of captopril treatment, are summarized in table 3 and figures 1 and 2.…”

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confidence: 99%

Renal artery stenosis with normal angiotensin II values. Relationship between angiotensin II and body sodium and potassium on correction of hypertension by captopril and subsequent surgery.

Atkinson¹,

Brown²,

Davies³

et al. 1981

Hypertension

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SUMMARYThe case is reported of a young woman with severe hypertension, unilateral renal artery stenosis, variously normal or marginally high plasma concentrations of active renin, angiotensin II, aldosterone, sodium, and potassium; and normal total exchangeable and total body sodium and potassium. Arteriograms and ureter catheterization showed the stenosis to be severe, but the unstimulated renal vein renin and angiotensin II differential to be modest. Captopril caused an initial fall in angiotensin II and arterial pressure. During prolonged captopril treatment, plasma angiotensin II and aldosterone remained depressed; exchangeable and total body sodium and potassium were unaltered. Blood pressure fell further to normal levels during prolonged captopril treatment, while subsequent surgical correction of the renal artery stenosis was curative; absolute values of blood pressure and plasma angiotensin II were similar in both situations.

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Measurement of total body potassium with a shadow shield whole-body counter: calibration and errors

Cited by 71 publications

References 9 publications

A Comparison of the Fat-Free Mass of Young Adults Estimated by Anthropometry, Body Density and Total Body Potassium Content

A Comparison of the Fat-Free Mass of Young Adults Estimated by Anthropometry, Body Density and Total Body Potassium Content

Energy balance in patients with advanced NSCLC, metastatic melanoma and metastatic breast cancer receiving chemotherapy – a longitudinal study

Renal artery stenosis with normal angiotensin II values. Relationship between angiotensin II and body sodium and potassium on correction of hypertension by captopril and subsequent surgery.

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