Measurement properties of the Timed Up &amp; Go test in patients with COPD

Mesquita, Rafael; Wilke, Sarah; Smid, Dionne E.; Janssen, Daisy J.A.; Franssen, Frits M.E.; Probst, Vanessa Suziane; Wouters, Emiel F.M.; Muris, Jean; Pitta, Fábio; Spruit, Martijn A.

doi:10.1177/1479972316647178

Cited by 91 publications

(95 citation statements)

References 36 publications

(75 reference statements)

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“…Therefore, the TUG test could be implemented in cases of COPD with more severe ventilatory impairment. Similarly, a cut-off point (11.2 s) different from the EWGSOP2 recommendation (20 s) has been suggested for use as an abnormal TUG time for COPD patients [66]. Nevertheless, additional studies are needed to establish which functional test and cut-offs should be used across different stages of COPD.…”

Section: Sarcopenia Consensus Statementsmentioning

confidence: 99%

Sarcopenia in COPD: a systematic review and meta-analysis

et al. 2019

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COPD is associated with a progressive loss of muscle mass and function. However, there is an unmet need to define and standardise methods to estimate the prevalence of sarcopenia in COPD patients.We performed a systematic review and meta-analysis of the prevalence of this extrapulmonary manifestation in COPD patients. We searched Embase, Medline (Ovid), CINAHL (EBSCO), Web of Science, Scopus and Google Scholar for studies published up to January 17, 2019, assessing sarcopenia in COPD patients based on low muscle mass and decreased muscle function. Interventional studies, in vitro experiments, protocols or reviews and meta-analyses were excluded. We estimated heterogeneity (I2) and assessed significance (Q) using a Chi-squared test for estimates obtained from random-effects models.4465 articles were initially identified. After removing the duplicates and applying the selection criteria, we reviewed 62 full-text articles. Finally, 10 articles (n=2565 COPD patients) were included in this systematic review and meta-analyses. Overall, the prevalence of sarcopenia in patients with COPD was 21.6% (95% CI 14.6–30.9%, I2=94%), ranging from 8% in population-based to 21% in clinic-based studies, and 63% in COPD patients residing in nursing homes.Sarcopenia is frequently observed in COPD patients, with varying prevalence across population settings. Sarcopenia in COPD should be assessed using standardised tests and cut-off points from sarcopenia consensus criteria for clinical practice and international comparisons.

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Section: Sarcopenia Consensus Statementsmentioning

confidence: 99%

Sarcopenia in COPD: a systematic review and meta-analysis

et al. 2019

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“…Several measures of balance are available, and some have been used in PR programmes . Other measures of exercise ability such as the timed up‐and‐go test, sit‐to‐stand test and measures of arm strength and endurance focus on patients' ability to perform ADL. Most studies of these measures have been done among patients with COPD.…”

Section: Patient Assessment and Outcomes Measurement In Prmentioning

confidence: 99%

Patient assessment and selection for pulmonary rehabilitation

Rochester

2019

Respirology

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Pulmonary rehabilitation (PR) is beneficial for people with several forms of chronic respiratory disease. Given the existing limitations on availability of PR services, it is important to identify participants who are most likely to benefit from it. Identification of criteria for patient referral to PR is challenging, as chronic respiratory diseases and their medical and psychosocial co‐morbidities place a complex and multifaceted burden on patients. Although research studies have attempted to identify key parameters predictive of ‘responsiveness to PR’, to date no firm physiological, psychosocial or other criteria exist by which optimal patient candidacy can be determined. Moreover, individual factors do not reliably predict successful multidimensional PR outcomes. In general, individuals who remain symptomatic with dyspnoea, fatigue and exercise intolerance; who have difficulty performing activities of daily living (ADL); and who are having difficulty coping with or managing their disease despite optimized pharmacological therapy are potential candidates for PR. Patient assessment and outcome measurement are core essential features of PR. To be considered as a PR programme, rehabilitation programmes must demonstrate, at a minimum, assessment and outcome measurement in regard to exercise capacity, dyspnoea and health‐related quality of life. Additional parameters, including physical activity, nutritional status, tobacco use status, patient knowledge and self‐efficacy, performance of ADL, fatigue, disease exacerbations, hospitalizations and other urgent healthcare utilization, and behavioural outcomes, including coping styles, patient satisfaction and programme metrics, are other relevant and important aspects of patient assessment and outcome measurement that should be considered and undertaken in PR, where feasible.

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“…All patients were enrolled in a comprehensive PR programme, as previously described [20]. Patients attended a 40-session programme which consisted, in brief, of high-intensity progressive exercise training (i.e., endurance and strength training); nutritional support, occupational therapy and psychological counselling, if indicated; and 20 1-hour educational group sessions.…”

Section: Pulmonary Rehabilitation Programmementioning

confidence: 99%

Changes in physical activity and sedentary behaviour following pulmonary rehabilitation in patients with COPD

Mesquita

Meijer

Pitta

et al. 2017

Respiratory Medicine

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A more profound investigation about the responses in activity levels following pulmonary rehabilitation (PR) in patients with COPD is needed. We aimed to describe groups of patients with COPD according to patterns of change in physical activity and sedentary behaviour following PR. 90 patients with COPD (60% male; mean age 67 ± 8; median FEV 47 (32-62) %pred) completed a comprehensive PR programme. A triaxial accelerometer was used to assess the time in sedentary behaviour, light activities and moderate-to-vigorous physical activity (MVPA). Additionally, exercise capacity, quality of life, and symptoms of anxiety and depression were assessed before and after PR. Six groups with different patterns of change in physical activity and sedentary behaviour were identified. The two most prevalent patterns were represented by good responders (increase in physical activity and reduction in sedentary behaviour, 34%) and poor responders (decrease in physical activity and increase in sedentary behaviour, 30%). Good responders had greater improvements in six-minute walk distance (6MWD) and symptoms of depression than poor responders (P < 0.05 for all). Strong correlation was found between changes in sedentary behaviour and changes in light activities (r = -0.89; P < 0.0001). Changes in 6MWD correlated fairly with changes in sedentary behaviour (r = -0.26), light activities (r = 0.25), and MVPA (r = 0.24); P < 0.05 for all. Different patterns of change in activity levels following PR can be found in patients with COPD. Focusing on light physical activities might be a potential strategy to make patients less sedentary, but for this to be achieved prior (or at least parallel) improvements in functional capacity seem to be necessary.

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Measurement properties of the Timed Up & Go test in patients with COPD

Cited by 91 publications

References 36 publications

Sarcopenia in COPD: a systematic review and meta-analysis

Sarcopenia in COPD: a systematic review and meta-analysis

Patient assessment and selection for pulmonary rehabilitation

Changes in physical activity and sedentary behaviour following pulmonary rehabilitation in patients with COPD

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