Measurements of intrafraction motion and interfraction and intrafraction rotation of prostate by three-dimensional analysis of daily portal imaging with radiopaque markers

Aubry, Jean‐François; Beaulieu, Luc; Girouard, Louis-Martin; Aubin, Sylviane; Tremblay, Daniel; Laverdière, Jacques; Vigneault, Éric

doi:10.1016/j.ijrobp.2004.02.045

Cited by 153 publications

(110 citation statements)

References 15 publications

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“…15 In most of these studies, daily fiducial marker based set-up corrections had been done and the target margin had been evaluated according to the prostate movement. 12,14,16 In this study, we found that the SV motion was significantly more in the AP axis and the distal part of SV. At least 7 mm PTV margin was required in the posterior direction.…”

Section: Discussionsupporting

confidence: 51%

“…[8][9] In the literature, the prostate motion has been well described while SV motion and dosimetric analysis have been relatively less well reported. [10][11][12][13][14][15][16][17][18] When the SV are included in the target volume, independent motion and the rotation of the SV and prostate may affect the dose distribution of the SV in prostate based image guidance. Stenmark et al showed that the displacement of the SV was different from the prostate and this movement was more in the distal part rather than the proximal part of SV.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Evaluation of Interfractional Movement of the Seminal Vesicle and Dose Variations with IGRT Throughout the Prostate Cancer Radiotherapy.

Ergen¹

2016

UHOD

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To validate the actual cumulative doses delivered to the seminal vesicle (SV) depending on the organ movement using kV-Cone Beam CT (kV-CBCT) datasets acquired during prostate image-guided radiation therapy. Ten patients with intermediate risk prostate cancer treated with IMRT were included in this study. Both the prostate and the first 2 cm of the SV were included in the CTV. PTV margin was 8 mm in all directions except posterior, where it was 5 mm. Sixteen kV-CBCT scans per patient were used for assessments. After each kV-CBCT was matched with the planning CT based on prostate, the SV were recontoured as proximal, distal SV and both of them together (the whole SV). Actual delivered doses to the SV were assessed by means of DVH. The variations in certain dosevolume parameters were analyzed using the Student's test. Systematic and random errors of the SV and margins were assessed using the van-Herk formula. We observed that the SV movement in the anterior-posterior direction was significantly more compared to superior-inferior and left-right direction. The dose volume variations for the whole SV (D98%, D50%, D2%) and the distal SV (D98%, D95%, D50%) were significantly different than the planned doses. However, both the whole SV and the distal SV received the prescribed dose. Although it seems that there is a need to give larger margin to the SV in posterior direction, the actual cumulative doses delivered to SV throughout the treatment were within the prescribed dose.Keywords: Image guided radiation therapy, Interfraction motions, kV-CBCT, Prostate cancer, Seminal vesicle ÖZET Prostat kanseri Radyoterapisi Sırasında Fraksiyonlar Arası Seminal Vezikül Hareketleri ve Doz Değişimlerinin IGRT ile DeğerlendirilmesiBu çalışmanın amacı, kV-Cone Beam CT (kV-CBCT) ile görüntü kılavuzluğunda prostat kanseri radyoterapisinde organ hareketine bağlı olarak seminal veziküllerin aldığı kümülatif dozların doğruluğunun değerlendirilmesidir. Çalışmamıza IMRT tekniği ile tedavi edilmiş orta risk prostat kanserli on hasta dahil edilmiştir. Prostat ve seminal vesiküllerin ilk 2 cm'lik bölümü CTV'ye dahil edilmiştir. Prostat ve SV'e posterior yönden 5 mm, diğer yönlerden 8 mm PTV marjı verilmiştir. Her hastadan 16 kV-CBCT alınmış ve SV'ye verilen marjın yeterli olup olmadığını saptamak için seçilen kV-CBCT görüntüleri ile planlama BT görüntüleri prostat referans alınarak offline eşleştirilmiştir. Seminal veziküller, proksimal-distal SV şeklinde ayrı ayrı ve her ikisi birlikte tüm SV olacak şekilde yeniden konturlanmıştır. Seminal veziküllerin aldığı doz DVH yardımı ile değerlendirilmiştir. Doz volüm histogramındaki değişiklikler Student test ile analiz edilmiştir. Sistematik ve random hatalar van-Herk formülü ile değerlendirilerek gerekli emniyet marjları bulunmuştur. Seminal vezikül hareketinin alt-üst ve sağ-sol yöne kıyasla ön-arka eksende daha fazla olduğu görülmüştür. Tüm SV için (D98% D50,% D2%) ve distal SV için doz volüm değişiklikleri (D98% D95,% D50%) planlanan dozlardan önemli ölçüde farklı bulunmuştur. Bununla bir...

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Section: Discussionsupporting

confidence: 51%

Section: Introductionmentioning

confidence: 99%

Evaluation of Interfractional Movement of the Seminal Vesicle and Dose Variations with IGRT Throughout the Prostate Cancer Radiotherapy.

Ergen¹

2016

UHOD

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“…The first reported clinical investigations of FFF referred to radiosurgery1 and aimed for shorter treatment times. A reduction of the treatment time reduces the probability of intrafraction motion of the target and organs at risk, which has been demonstrated to be not negligible for the treatment of prostate cancer 2, 3, 4, 5, 6, 7, 8. Another property of FFF is the diminution of head scatter, as the flattening filter is one of its main sources 9, 10.…”

Section: Introductionmentioning

confidence: 99%

Volumetric‐modulated arc therapy and intensity‐modulated radiation therapy treatment planning for prostate cancer with flattened beam and flattening filter free linear accelerators

Treutwein¹,

Hipp

Koelbl³

et al. 2017

J Applied Clin Med Phys

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This study on patients with localized prostate cancer was set up to investigate valuable differences using flattened beam (FB) and flattening filter free (FFF) mode in the application of intensity‐modulated radiotherapy (IMRT) and volumetric‐modulated arc therapy (VMAT). For ten patients, four different plans were calculated with Oncentra planning system of Elekta, using Synergy machines: IMRT and VMAT, with and without flattening filter. Homogeneity and conformity indexes, dose to the organs at risk, and measurements of peripheral dose and dosimetric plan verification including record of the delivery times were analyzed and statistically evaluated. The indexes for homogeneity and conformity (CTV and PTV) are either advantageous or not significantly different for FFF compared to FB with one minor exception. Regarding the doses to the organs at risk and the measured peripheral dose, equivalent or lower doses were delivered for FFF than with FB. Furthermore, the delivery times were significantly shorter for FFF. VMAT compared to IMRT reveals benefits or at least equivalent values. VMAT‐FFF combines the most advantageous plan quality parameters with the shortest delivery times and reduced peripheral dose and is therefore recommended for the given equipment and cancer localization.

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“…[10][11][12][13][14] In contrast, intrafraction motion refers to the motion of the patient and/or internal organs during delivery of a treatment fraction. A number of authors have investigated internal organ motion in a variety of tumor sites, including lung, 15 liver, [16][17][18] prostate, 19,20 and breast. [21][22][23] These studies indicate that internal anatomy can move significantly in time intervals corresponding to the duration of a radiation fraction.…”

mentioning

confidence: 99%

Quality assurance for nonradiographic radiotherapy localization and positioning systems: Report of Task Group 147

Willoughby

Lehmann

Bencomo³

et al. 2012

Medical Physics

112

126

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New technologies continue to be developed to improve the practice of radiation therapy. As several of these technologies have been implemented clinically, the Therapy Committee and the Quality Assurance and Outcomes Improvement Subcommittee of the American Association of Physicists in Medicine commissioned Task Group 147 to review the current nonradiographic technologies used for localization and tracking in radiotherapy. The specific charge of this task group was to make recommendations about the use of nonradiographic methods of localization, specifically; radiofrequency, infrared, laser, and video based patient localization and monitoring systems. The charge of this task group was to review the current use of these technologies and to write quality assurance guidelines for the use of these technologies in the clinical setting. Recommendations include testing of equipment for initial installation as well as ongoing quality assurance. As the equipment included in this task group continues to evolve, both in the type and sophistication of technology and in level of integration with treatment devices, some of the details of how one would conduct such testing will also continue to evolve. This task group, therefore, is focused on providing recommendations on the use of this equipment rather than on the equipment itself, and should be adaptable to each user's situation in helping develop a comprehensive quality assurance program.

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Measurements of intrafraction motion and interfraction and intrafraction rotation of prostate by three-dimensional analysis of daily portal imaging with radiopaque markers

Cited by 153 publications

References 15 publications

Evaluation of Interfractional Movement of the Seminal Vesicle and Dose Variations with IGRT Throughout the Prostate Cancer Radiotherapy.

Evaluation of Interfractional Movement of the Seminal Vesicle and Dose Variations with IGRT Throughout the Prostate Cancer Radiotherapy.

Volumetric‐modulated arc therapy and intensity‐modulated radiation therapy treatment planning for prostate cancer with flattened beam and flattening filter free linear accelerators

Quality assurance for nonradiographic radiotherapy localization and positioning systems: Report of Task Group 147

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