DOI: 10.1159/000403053
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Measurements of Mucociliary Clearance with 99mTc-Tagged Erythrocytes1

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Cited by 18 publications
(10 citation statements)
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“…The radionuclide 'W mTc, chelated to DTPA (mean diameter. 0.8 urn, Sorin-Saluggia, Italy) was inhaled as an aerosol produced with the Matthys apparatus [13]. Compressed air, produced by a small compressor, goes through a screened neb ulizer where the saline-diluted radionuclide is placed.…”
Section: Methodsmentioning
confidence: 99%
“…The radionuclide 'W mTc, chelated to DTPA (mean diameter. 0.8 urn, Sorin-Saluggia, Italy) was inhaled as an aerosol produced with the Matthys apparatus [13]. Compressed air, produced by a small compressor, goes through a screened neb ulizer where the saline-diluted radionuclide is placed.…”
Section: Methodsmentioning
confidence: 99%
“…The organic particles for aerosol studies were (1) autologous erythrocytes prepared as spherocytes (mean diameter 4±0.4/tm) [1] and (2) HAM (7-25 /tm in diameter; TCK-5-S; Sorin).…”
Section: Methodsmentioning
confidence: 99%
“…Saluggia, Vercelli (Italy) and autologous erythrocytes [1] are or ganic particles used for lung mucociliary clearance measurements in human sub jects [2]. These particles are considered to be real sponges for radionuclides as 99mTc.…”
Section: Introductionmentioning
confidence: 99%
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“…Physiologists have studied mucociliary function in the trachea. However, with the development of fine bronchofiberscopes [Sackner et al, 1973] (2-amino-3,5-dibromobenzyl) amine (Wulfing, Neuss, FRG) ii Tachoquilin® = oxyethyl-tert-octyl-phenol-formaldehyde polymer (Pohl-Boskamp, Hohenlockstedt/HoIstein, FRG) iii Sobrepin® = tyloxapol + glycerin + Na-hydrogencarbonate D Miscellaneous substances i Ammonium chloride (NH4C1) ii Potassium iodide (Kl) iii Prostaglandin E, (PGE,) radiotagging of particles [Ruhle et al, 1979] and in vitro techniques involving dissection of the entire tracheobronchial tree [Iravani, 1967; knowledge of this im portant aspect of tracheobronchial clear ance and the factors that enhance or inhibit it has increased. The present paper reports data on: (a) mucociliary function in health and disease, and (b) the effect of mucolytic substances on mucociliary function.…”
Section: Introductionmentioning
confidence: 99%