We report a direct detection of muon-induced high energy neutrons with a 12-liter neutron detector fabricated with EJ-301 liquid scintillator operating at Soudan Mine for about two years. The detector response to energy from a few MeV up to ∼ 20 MeV has been calibrated using radioactive sources and cosmic-ray muons. Subsequently, we have calculated the scintillation efficiency for nuclear recoils, up to a few hundred MeV, using Birks' law in the Monte Carlo simulation. Data from an exposure of 655.1 days were analyzed and neutron-induced recoil events were observed in the energy region from 4 MeV to 50 MeV, corresponding to fast neutrons with kinetic energy up to a few hundred MeV, depending on the scattering angle. Combining with the Monte Carlo simulation, the measured muon-induced fast neutron flux is determined to be (2.23 ± 0.52(sta.) ± 0.99(sys.)) × 10 −9 cm −2 s −1 (En > 20 MeV), in a reasonable agreement with the model prediction. The muon flux is found to be (1.65 ± 0.02(sta.) ± 0.1(sys.)) × 10 −7 cm −2 s −1 (Eµ > 1 GeV), consistent with other measurements. As a result, the muon-induced high energy gamma-ray flux is simulated to be 7.08 ×10 −7 cm −2 s −1 (Eγ > 1 MeV) for the depth of Soudan.