The study of photoproduction reactions has gained a unique opportunity with the HERA data. The high center of mass energy allows to carry out quantitative tests of QCD, to explore the substructure of both the photon and the proton and to shed new light on soft and diractive processes. In this report we review the HERA results, comparing them with the reach of xed target photoproduction experiments and complementary measurements from e + e and hadron colliders.