Measures of fatigue: Bristol Rheumatoid Arthritis Fatigue Multi‐Dimensional Questionnaire (BRAF MDQ), Bristol Rheumatoid Arthritis Fatigue Numerical Rating Scales (BRAF NRS) for Severity, Effect, and Coping, Chalder Fatigue Questionnaire (CFQ), Checklist Individual Strength (CIS20R and CIS8R), Fatigue Severity Scale (FSS), Functional Assessment Chronic Illness Therapy (Fatigue) (FACIT‐F), Multi‐Dimensional Assessment of Fatigue (MAF), Multi‐Dimensional Fatigue Inventory (MFI), Pediatric Quality Of Life (Pe

Hewlett, Sarah; Dures, Emma; Almeida, Celia

doi:10.1002/acr.20579

Cited by 330 publications

(192 citation statements)

References 113 publications

(427 reference statements)

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“…For women, low grip strength was defined as: ≤17 for BMI <23, ≤17.3 for BMI 23.1-26, ≤18 for BMI 26.1-29, ≤21 BMI>29. The fatigue severity subscale of the Multidimensional Assessment of Fatigue was used to assess fatigue; scores range from 0–10 (where 0 = no fatigue and 10 = most severe fatigue) [18]. A score ≥ 7 was classified as severe fatigue.…”

Section: Methodsmentioning

confidence: 99%

Frailty and reduced physical function go hand in hand in adults with rheumatoid arthritis: a US observational cohort study

et al. 2017

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Objective Reduced physical function and health-related quality of life are common in Rheumatoid Arthritis (RA), and further studies are needed that examine novel determinates of reduced physical function in RA. This study examines whether frailty, a state of increased vulnerability to stressors, is associated with differences in self-reported physical function among adults with RA. Methods Adults from a longitudinal RA cohort (n=124) participated in the study. Using an established definition of frailty, individuals with 3 or more of the following physical deficits were classified as frail: 1) body mass index ≤ 18.5, 2) low grip strength (adjusted for sex and BMI, measured by handheld dynamometer), 3) severe fatigue (measured by the Multidimensional Assessment of Fatigue), 4) slow 4-meter walking speed (adjusted for sex and height), 5) low physical activity (measured by the International Physical Activity Questionnaire). Individuals with 1 or 2 deficits were classified as “pre-frail”, and those with no deficits as “robust.” Self-reported physical function was assessed by the Health Assessment Questionnaire (HAQ) and the Valued Life Activities Difficulty scale. Regression analyses modeled associations of frailty category with HAQ and VLA Difficulty scores with and without controlling for age, sex, disease duration, C-reactive protein, use of oral steroids, and pain. Results Among adults with RA, being frail compared to being robust was associated with a 0.44 worse VLA score (p<0.01) when the effects of covariates are held constant. Conclusions Being frail, compared to being robust, is associated with clinically meaningful differences in self-reported physical function among adults with RA.

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Section: Methodsmentioning

confidence: 99%

Frailty and reduced physical function go hand in hand in adults with rheumatoid arthritis: a US observational cohort study

et al. 2017

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“…Fatigue VAS have been criticized for lack of standardization because this causes great difficulty with comparisons across studies (68). …”

Section: Patient Report Outcomes In Psoriatic Arthritis Studiesmentioning

confidence: 99%

Patient-Reported Outcomes in Psoriatic Arthritis

Orbai¹,

Ogdie²

2016

Rheumatic Disease Clinics of North America

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SYNOPSIS Patient reported outcome (PRO) measures are an important component to assessing disease impact and therapy response in patients with psoriatic arthritis (PsA). Overall there are few PsA-specific PROs. Most PROs used in PsA are borrowed from other diseases (e.g. rheumatoid arthritis and ankylosing spondylitis) or general population PROs. PROs are used in PsA clinical trials and in the clinical management of PsA. In this review, we discuss the most commonly used PRO in PsA including their inclusion in composite measures. Future studies may be helpful to determine the best performing PROs in patients with PsA.

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“…The VAS (100 mm) fatigue involves the severity of the fatigue over the past week with the anchors: no fatigue (0 mm) and extremely fatigued (100 mm). The scale is sensitive to change, valid, and reliable, but no cut-off point has been determined [21, 22]. The FAS is a ten-item fatigue scale with a good internal consistency, reliability, and validity [23, 24].…”

Section: Methodsmentioning

confidence: 99%

Fatigue in early, intensively treated and tight-controlled rheumatoid arthritis patients is frequent and persistent: a prospective study

et al. 2018

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Fatigue has a large impact on quality of life and is still unmanageable for many patients. Study aims were describe (1) the prevalence and pattern of fatigue over time in patients with early rheumatoid arthritis under a treat-to-target strategy and (2) identify predictive factors for worsening and recovering of fatigue over time. Data from the tREACH study were used, comparing different treatment strategies with fatigue as secondary objective. Patient outcomes on fatigue, quality of life, depression, and coping were obtained every 6 months and clinically assessed every 3 months. Prediction of fatigue at 12 months was investigated with an ROC curve. Analysis was stratified into non-fatigue and fatigue at baseline. Logistic regression was used for the evolution of fatigue in relation with the covariates over time. Almost half of all patients (n = 246) had high fatigue levels at baseline, decreasing slightly over time. At 12 months, 43% of patients were fatigued; while 23% of the initially fatigued patients showed lower levels of fatigue, the fatigue level had increased in 15% of the initially non-fatigued patients. The strongest predictor of fatigue was the previous fatigue levels (AUC 0.89). Higher score on the depression scale and coping with limitations was associated with developing fatigue over time in the initially non-fatigued group. Despite a strict treat-to-target strategy, fatigue remained an overall problem during the first year of treatment, and was mainly predicted by its baseline status. In subgroups, a small additional effect of depression was seen. Monitoring fatigue and depression may be important in managing fatigue.

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Cited by 330 publications

References 113 publications

Frailty and reduced physical function go hand in hand in adults with rheumatoid arthritis: a US observational cohort study

Frailty and reduced physical function go hand in hand in adults with rheumatoid arthritis: a US observational cohort study

Patient-Reported Outcomes in Psoriatic Arthritis

Fatigue in early, intensively treated and tight-controlled rheumatoid arthritis patients is frequent and persistent: a prospective study

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