The organizational reflex in relation to the company is considered to be an instinctive reaction of its employees to an external stimulus that has arisen or, in other words, the ability of the employee to spontaneously generate a competitive response of the company based on the information received from the global environment. It is an intentional algorithm that enables employees to know how and when to react as quickly as possible, according to the signal from the global environment received, within the limits of their area of expertise. This response phenomenon comes forth in the context of the functioning of a sustainable organization and highlights the coherence of the performance of a human resource. In order to maintain its competitiveness, each organization learns to react to the ongoing changes in the dynamic environment as quickly as possible and, in this process, develops action algorithms similar to human reflexes in structure. Modern science makes a great contribution to the longevity of the company by creating activity models for the organization and performing simulations in the digital space. In this paper, the simulation model of a company’s competitive human resource response to global changes, which is used for the description of organizational reflex, is present. The model reflects the human reflex arc in a company’s decision-making process, whose effectiveness depends on the coherence of its human resources and its ability to sustain an effective organizational reflex. The purpose of the developed model is to simulate the employee’s response to the signals incoming from the global environment and to describe the development process of the organizational reflex that is leading to the longevity of the company and the sustainability of its market leadership.