Measuring and Evaluating Function, Impairment, and Change with Intervention

Fried, Robert

doi:10.1016/b978-0-12-420046-3.00002-0

Cited by 5 publications

(3 citation statements)

References 90 publications

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“…The augmentation index (AIx) is the measure of the enhancement of central aortic pressure by a reflected pulse wave. It is correlated with PWV and is a valid measure of AS [35]. The carotid intima-media thickness (cIMT) does not measure AS itself, but is strongly correlated with changes in PWV [36].…”

Section: Arterial Stiffness and Measurement Methodsmentioning

confidence: 99%

Arterial stiffness: a possible predictor of atrial fibrillation

Farina¹,

Kalil²,

Gutiérrez³

et al. 2022

Rev. Cardiovasc. Med.

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Atrial fibrillation (AF) is the most common cardiac arrhythmia, affecting 0.5%-1% of people worldwide. Hemodynamic changes due to stiffening of the arteries may cause cardiac structural and electrical remodeling that induces AF.Pulse wave velocity (PWV) is a direct non-invasive method to measure arterial stiffness (AS). Central pulse pressure (PPc) describes oscillations around the mean arterial pressure and is increased in more rigid arteries. These two central variables can be considered markers of AF. Sympathetic activity has been reported to be directly relatedto PWV even in patients without comorbidities. Therefore, in patients with more rigid arteries, sudden changes in pressure could affect the activation of arterial baroreceptors, leading to an acute imbalance between the sympathetic and parasympathetic responses in the heart. The coexistence of AF and AS is common. This critical review aims to bring information about the role of AS in the pathophysiology of AF and discuss results of clinical studies on this topic. Althuogh discussed in the literature, further studies are needed to confirm the predictive role of these variables in AF, and their use in clinical practice.

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Section: Arterial Stiffness and Measurement Methodsmentioning

confidence: 99%

Arterial stiffness: a possible predictor of atrial fibrillation

Farina¹,

Kalil²,

Gutiérrez³

et al. 2022

Rev. Cardiovasc. Med.

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“…Аугментационният индекс се дължи на отразената пулсова вълна и по стойностите му може да се съди за физичните свойства на съдовата стена и по-специално за ригидността на аортата. Индексите, които отразяват характеристиките на отразената вълна (като АІ), представляват независим предсказващ фактор за развитие на ССЗ (58).…”

Section: артериална ригидностunclassified

Endothelial dysfunction in beta-thalassemia

Petrova

2023

vmf

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Съдовият ендотел е динамична ендокринна структура, която участва активно в поддържането на съдовата хомеостаза. Ендотелната дисфункция е маркер за съдова увреда, която обикновено стои в основата и дава началото на сърдечно-съдовите заболявания. Установяването на ендотелната дисфункция има голямо клинично значение и може да се докаже чрез изследване на различни клетъчни маркери или чрез функционални проби.Артериалната ригидност възниква в резултат на ендотелно увреждане. Нейното установяване е в помощ при диагностицирането на атеросклерозата и сърдечно-съдовите болести и е маркер за повишена сърдечно-съдова заболеваемост и смъртност. Един от основните методи за оценка на артериалната ригидност е измерването на скоростта на пулсовата вълна, която е независим рисков фактор за бъдещи сърдечно-съдови събития и обща смъртност.При пациентите с бета-таласемия майор (БТМ) свързаната със свободното желязо пероскидативна тъканна увреда е асоциирана с висок риск от развитие на ендотелна дисфункция и артериална ригидност. Увеличената продължителност на живота и тревожното разпространение на класическите сърдечно-съдови рискови фактори като диабет, артериална хипертония и тютюнопушене водят до повишен риск от настъпване на акцелерирана атеросклероза и сърдечно-съдови заболявания при пациентите с БТМ.Оценката на съдовата увреда и оксидативният стрес при пациентите с БТМ продължава да е обект на многоцентрови изследвания пора-

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“…The main parameter used to assess AS is the pulse wave velocity (PWV), as estimated by noninvasive methods, such as the carotid-femoral PWV. An indirect measure of AS can be achieved by using the augmentation index (AI), which measures the augmentation of central aortic pressure by a reflected pulse wave ( 55 ). CV risk assessment in chronic inflammatory and autoimmune diseases should also rely on PWV and AI, however this recommendation was not formulated based on studies including SS patients ( 52 ).…”

Section: Cardiovascular Involvement In Sjogren’s Syndromementioning

confidence: 99%

Cardiovascular Disease in Primary Sjögren’s Syndrome: Raising Clinicians’ Awareness

Casian

Jurcuţ²,

Dima

et al. 2022

Front. Immunol.

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In the ever evolving landscape of systemic immune mediated diseases, an increased awareness regarding the associated cardiovascular system impairment has been noted in recent years. Even though primary Sjögren’s Syndrome (pSS) is one of the most frequent autoimmune diseases affecting middle-aged individuals, the cardiovascular profile of this specific population is far less studied, at least compared to other autoimmune diseases. Traditional cardiovascular risk factors and disease specific risk factors are inextricably intertwined in this particular case. Therefore, the cardiovascular risk profile in pSS is a multifaceted issue, sometimes difficult to assess. Furthermore, in the era of multimodality imaging, the diagnosis of subclinical myocardial and vascular damage is possible, with recent data pointing that the prevalence of such involvement is higher in pSS than in the general population. Nevertheless, when approaching patients with pSS in terms of cardiovascular diseases, clinicians are often faced with the difficult task of translating data from the literature into their everyday practice. The present review aims to synthesize the existing evidence on pSS associated cardiovascular changes in a clinically relevant manner.

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Measuring and Evaluating Function, Impairment, and Change with Intervention

Cited by 5 publications

References 90 publications

Arterial stiffness: a possible predictor of atrial fibrillation

Arterial stiffness: a possible predictor of atrial fibrillation

Endothelial dysfunction in beta-thalassemia

Cardiovascular Disease in Primary Sjögren’s Syndrome: Raising Clinicians’ Awareness

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