Measuring and identifying large-study metrics for circadian rhythm disruption in female flight attendants

Grajewski, Barbara; Nguyen, Mimi; Whelan, Elizabeth A.; Cole, Roger J.; Hein, Misty J.

doi:10.5271/sjweh.740

Cited by 45 publications

(36 citation statements)

References 29 publications

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“…Our characterization of circadian disruption is, to our knowledge, the first comprehensive long-term assessment of its kind in this occupational group. We used non-directional time zones crossed as an exposure metric because time zones are well correlated with a state of chronic disruption as biologically measured by an increase in the overnight variability of melatonin excretion in female flight attendants (Grajewski et al, 2003). We also assessed SSI travel because it captures the separate but related exposure of sleep disturbance rather than the desynchronization reflected in cumulative time zones crossed (Grajewski et al, 2003).…”

Section: Discussionmentioning

confidence: 99%

“…Number of SPEs was assessed separately with reference to satellite data for 23 moderate or large events during the study period. To assess circadian disruption, non-directional cumulative time zones crossed and standard sleep interval (SSI) travel, a separate measure of sleep disturbance, were calculated (Grajewski et al, 2003).…”

Section: Methodsmentioning

confidence: 99%

“…Flight crew also experience chronic circadian rhythm disruption when their typical work schedule requires flying across multiple time zones or working during their normal sleep hours, a form of shiftwork (Grajewski et al, 2003). Recent research indicates that the molecular circadian clock, which sets rates and periodicity for many biochemical functions, also modulates cellular response to DNA repair (Sancar et al, 2010).…”

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confidence: 99%

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Airline Pilot Cosmic Radiation and Circadian Disruption Exposure Assessment from Logbooks and Company Records

Grajewski

Waters

Yong

et al. 2011

The Annals of Occupational Hygiene

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Objectives: US commercial airline pilots, like all flight crew, are at increased risk for specific cancers, but the relation of these outcomes to specific air cabin exposures is unclear. Flight time or block (airborne plus taxi) time often substitutes for assessment of exposure to cosmic radiation. Our objectives were to develop methods to estimate exposures to cosmic radiation and circadian disruption for a study of chromosome aberrations in pilots and to describe workplace exposures for these pilots.Methods: Exposures were estimated for cosmic ionizing radiation and circadian disruption between August 1963 and March 2003 for 83 male pilots from a major US airline. Estimates were based on 523 387 individual flight segments in company records and pilot logbooks as well as summary records of hours flown from other sources. Exposure was estimated by calculation or imputation for all but 0.02% of the individual flight segments' block time. Exposures were estimated from questionnaire data for a comparison group of 51 male university faculty.Results: Pilots flew a median of 7126 flight segments and 14 959 block hours for 27.8 years. In the final study year, a hypothetical pilot incurred an estimated median effective dose of 1.92 mSv (absorbed dose, 0.85 mGy) from cosmic radiation and crossed 362 time zones. This study pilot was possibly exposed to a moderate or large solar particle event a median of 6 times or once every 3.7 years of work. Work at the study airline and military flying were the two highest sources of pilot exposure for all metrics. An index of work during the standard sleep interval (SSI travel) also suggested potential chronic sleep disturbance in some pilots. For study airline flights, median segment radiation doses, time zones crossed, and SSI travel increased markedly from the 1990s to 2003 (P trend < 0.0001). Dose metrics were moderately correlated with records-based duration metrics (Spearman's r 5 0.61-0.69).Conclusions: The methods developed provided an exposure profile of this group of US airline pilots, many of whom have been exposed to increasing cosmic radiation and circadian disruption from the 1990s through 2003. This assessment is likely to decrease exposure misclassification in health studies.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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confidence: 99%

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Airline Pilot Cosmic Radiation and Circadian Disruption Exposure Assessment from Logbooks and Company Records

Grajewski

Waters

Yong

et al. 2011

The Annals of Occupational Hygiene

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“…For most self-respondents, absorbed dose (in mGy without radiation or tissue weighting factors applied) received during work flights while employed as a flight attendant by any airline and commuter flights (flights taken to the domicile to which the flight attendant was assigned) was estimated by linking domicile-and/ or era-specific absorbed dose rates with work history data obtained from interviews. SSI travel and number of time zones crossed were estimated in an analogous way using methods described elsewhere (8,9). For 195 cohort members without self-reported work history data from interviews, absorbed dose, SSI travel, and number of time zones crossed incurred during employment as a flight attendant at Pan Am and National airlines (which was purchased by Pan Am in 1981) only were estimated as described by Waters et al (9) using work history data obtained from the company records.…”

Section: Exposure Assessmentmentioning

confidence: 99%

Breast cancer incidence among female flight attendants: exposure–response analyses

Pinkerton¹,

Hein²,

Anderson³

et al. 2016

Scand J Work Environ Health

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“…Our investigation examines flight attendants, whose work environment comprises many challenging and age sensitive work conditions like work overload, circadian rhythm disruption, emotional and customer-related stressors, high information load, and intense demands for the musculoskeletal system (Griffiths and Powell 2012;Grajewski et al 2003). To inform occupational health interventions, further investigations are necessary to address the interplay of the work environment of flight crew personnel and factors that are beneficial to maintain well-being, performance, and capabilities (Griffiths and Powell 2012).…”

Section: Introductionmentioning

confidence: 99%

Erratum to: Weigl, M., Müller, A., Hornung, S., Leidenberger, M., Heiden, B.: Job resources and work engagement: the contributing role of selection, optimization, and compensation strategies at work

Weigl

Müller

Hornung

et al. 2015

J Labour Market Res

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Job resources and work engagement: the contributing role of selection, optimization, and compensation strategies at work Matthias Weigl · Andreas Müller · Severin Hornung · Max Leidenberger · Barbara Heiden engagement. additionally, we found meaningful mediation effects, such that positive associations of job resources with work engagement were significantly mediated through SOC use. These findings suggest that the application of successful aging strategies and enhanced job resources are conducive to engagement at work. Theoretical and practical implications regarding the joint effects of SOC strategies and job resources for successful aging in the workplace are discussed. Zusammenfassung Das Handlungsmodell der Selektion, Optimierung und Kompensation (SOK) hat sich als ein wichtiger ansatz zum Verständnis der Bewältigung von alters-und alternsbedingten Veränderungen bei Beschäf-tigten an ihrem arbeitsplatz herausgestellt. Bislang konnte die Forschung zeigen, dass Beschäftigte mit häufigen SOK-Strategien in der arbeit erfolgreiches altern am arbeitsplatz berichten. Gleichwohl sind die verantwortlichen arbeitsbedingungen für eine erfolgreichen SOK-anwendung unzureichend beleuchtet. unsere Studie untersuchte die direkten und indirekten Effekte für das Engagement in der arbeit durch die anwendung von SOK-Handlungsweisen am arbeitsplatz sowie durch zwei zentrale ressourcen der arbeit: Lern-und Entwicklungsmöglichkeiten sowie autonomie im Job. Diese Informationen wurden mittels AbstractThe life-span model of selection, optimization, and compensation (SOC) provides a valuable theoretical framework for understanding organizational behaviour related to coping with age-related changes. although previous research has demonstrated that SOC strategies at work contribute positively to individual outcomes, the role of workplace characteristics has been insufficiently addressed. This study investigated direct and indirect effects of SOC strategies at work and two important job resources (i.e., learning and developmental opportunities and autonomy at work) in predicting work engagement. all variables were assessed through employee self-reports based on standardized survey measures. Data collected from 118 flight attendants showed that SOC strategies were positively associated with work engagement (r = 0.28, p < 0.05). Learning and developmental opportunities (r = 0.35, p < 0.01) and job control (r = 0.31, p < 0.01) were also related to work Job resources and work engagement: the contributing role of selection, optimization, and compensation eines Fragebogen erfasst, anhand standardisierter Skalen. Die untersuchungsgruppe waren N = 118 Flugbegleiter verschiedener deutscher und österreichischer airlines. Die vermehrte anwendung von SOK Strategien ging mit hö-herem arbeitsengagement einher (r = 0.28, p < 0.05). Lernund Entwicklungsmöglichkeiten in der arbeit (r = 0.35, p < 0.01) und autonomie (r = 0.31, p < 0.01) waren gleichfalls mit mehr arbeitsengagement assoziiert. anhand von mediationsanalysen fanden wir, dass der positive Ef...

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Measuring and identifying large-study metrics for circadian rhythm disruption in female flight attendants

Abstract: Affiliation: NIOSH (R-13), 4676 Columbia Parway, Cincinnati, OH 45226, United States. bag2@cdc.govThe following article refers to this text: 2016;42(6):455-562

Cited by 45 publications

References 29 publications

Airline Pilot Cosmic Radiation and Circadian Disruption Exposure Assessment from Logbooks and Company Records

Airline Pilot Cosmic Radiation and Circadian Disruption Exposure Assessment from Logbooks and Company Records

Breast cancer incidence among female flight attendants: exposure–response analyses

Erratum to: Weigl, M., Müller, A., Hornung, S., Leidenberger, M., Heiden, B.: Job resources and work engagement: the contributing role of selection, optimization, and compensation strategies at work

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