Background:The delivery of high-quality maternal and neonatal care is challenging in low-and middle-income countries. This study assesses a program aimed at offering evidence-informed care and enhancing service utilization. Methods: Data on the number of births, neonatal mortality, infant survival, maternal mortality, postpartum infection, pelvic floor damage, and breastfeeding were collected and analyzed retrospectively from the Cloudnine Hospital Network (CHN; encompassing 29 hospitals) from January 2007 to January 2023. The CHN's comprehensive maternity program covers pre-delivery, delivery, and post-delivery stages with mandated antenatal classes led by a multidisciplinary team to educate couples about pregnancy. Post-delivery support includes consultations with physiotherapists, lactation consultants, and nutritionists. Results: The CHN's program has resulted in negligible maternal and neonatal mortality rates (2 per 100,000 deliveries and 2 per 1,000 live births, respectively), and a 99.8% infant survival rate for those born after 28 weeks of gestation. Post-partum infection rates were only 0.6% and significantly lower than in national average. Pelvic floor damages were rare, and 95% of mothers were breastfeeding at discharge. Conclusion: The CHN's comprehensive care program effectively reduces maternal and neonatal mortality rates. This article highlights the critical aspects of optimal maternal and neonatal care based on the experiences of the CHN.