Measuring Patient-Reported Health-Related Quality of Life in Velopharyngeal Insufficiency: Reliability and Validity of the Brazilian Portuguese Version of the VELO Instrument

Denadai, Rafael; Raposo-Amaral, Cássio Eduardo; Sabbag, Anelise; Ribeiro, Rafael Andrade; Buzzo, Celso Luiz; Raposo‐Amaral, Cesar Augusto; Hung, Man; Skirko, Jonathan R.

doi:10.1177/1055665619846763

Cited by 15 publications

(8 citation statements)

References 45 publications

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“…All patients underwent regular physical examinations at 1, 2, and 4 weeks and 3, 6, and 12 months after surgery, during which any sign of postoperative complication was observed. Speech assessment-related data 17,18 Plastic and Reconstructive Surgery • January 2022 were also collected. The principles outlined in the Declaration of Helsinki were followed.…”

Section: Methodsmentioning

confidence: 99%

Split Buccal Fat Flap in Modified Furlow Palatoplasty: Surgical Technique and Early Result

Denadai

2021

Plastic &Amp; Reconstructive Surgery

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Encouraging results have been described for the use of pedicled buccal fat pad flap in primary cleft palate repair. This retrospective study describes the surgical technique and early results of a technical innovation utilizing the split buccal fat flaps in modified Furlow palatoplasty with small double-opposing Z-plasty. This technique introduces buccal fat tissue for coverage of lateral denuded palate surfaces to reduce the bone exposure and scar formation to potentially attenuate maxillary growth interference and for reinforcement of the palatal areas of high tension or with incomplete closure to decrease the risk of postoperative dehiscence and oronasal fistula formation. Consecutive nonsyndromic patients (n = 56) with cleft palate were treated with this method, all of whom demonstrated fast mucosalization of lateral palatal recipient regions within 3 weeks postoperatively and showed no fistula with 12 months' follow-up. Of 19 patients (33.9 percent) who underwent auditory-perceptual assessment, 15 (78.9 percent) had normal resonance. Surgeons could add this alternative surgical maneuver to their armamentarium during the primary palatoplasty, in which coverage of lateral surfaces and reinforcement with fat tissue in the anterior soft palate space are of paramount relevance.

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Section: Methodsmentioning

confidence: 99%

Split Buccal Fat Flap in Modified Furlow Palatoplasty: Surgical Technique and Early Result

Denadai

2021

Plastic &Amp; Reconstructive Surgery

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“…For both univariate and multivariate analyses, P-values of< .05 were considered statistically significant. For secondary analyses, the Bonferroni P-value correction was applied, and the adjusted P value for statistical significance was .005 (Denadai et al, 2019).…”

Section: Discussionmentioning

confidence: 99%

“…Table 2 shows the relationship between the VELO total score and domains and the patients' age groups. Considering the age distribution of the patients, the patients were divided into 2 groups with a cut-off value of 8 years to evaluate the effects of age (Denadai et al, 2019).…”

Section: Analysis Of Study Variablesmentioning

confidence: 99%

Quality of Life in Patients With Velopharyngeal Insufficiency in West China

Yakupu

et al. 2021

The Cleft Palate Craniofacial Journal

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Objective This study aimed to investigate the quality of life (QOL) of patients with cleft lip and palate and velopharyngeal insufficiency (VPI) in relation to sex, age, age at initial cleft lip surgery, and age at initial cleft palate surgery. Design This is a cross-sectional study. Setting The study was conducted in a tertiary medical center. Participants The participants were caregivers of 72 patients with cleft lip and palate and VPI aged 4 to 20 years. Main Outcome Measure(s) Participants completed the Chinese version of the caregiver report of the VPI Effects on Life Outcomes (VELO) questionnaire. The Mann–Whitney U test was used to evaluate the patients’ sex, age, age at initial cleft lip repair, and age at initial cleft palate repair in relation to VELO total score and domains. Spearman correlation analysis was completed including all study variables. Associations between the study variables and the VELO total score were tested using a generalized linear mixed model. Results In the univariate analysis, patients’ age and age at initial cleft palate surgery influenced the QOL of patients with VPI. There were no differences in the VELO total score or domains based on sex or age at first cleft lip surgery. In the generalized linear mixed model, patients older than 8 years had higher VELO total scores. Conclusions By caregiver report, the QOL of patients under age 8 years with VPI was lower than older patients. In addition, the caregiver impact domain was higher for parents of children who had their initial cleft palate surgery at age 2 years or younger.

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“…Another way of understanding the clinical implications of VPI is through quality of life (QoL). Although the severity of VPI from blinded assessment is important, studies have found that those with any severity of VPI have QoL that is significantly worse than either patients with CP without VPI or normal controls (Denadai et al, 2019). Additionally, previous work identifying the association between VPI severity and QoL has shown a correlation but has also shown that those with any severity of VPI can have severely impaired QoL (Skirko et al, 2013; Bhuskute et al, 2017).…”

Section: Introductionmentioning

confidence: 99%

Increased Risk of Velopharyngeal Insufficiency in Patients Undergoing Staged Palate Repair

McCrary

Pollard

Torrecillas

et al. 2020

The Cleft Palate Craniofacial Journal

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Objective: To evaluate the association of 2-stage cleft palate (CP) surgery on velopharyngeal insufficiency (VPI) incidence, speech surgeries, and cleft-related surgical burden. Design: Retrospective cohort with follow-up of 4 to 19 years. Setting: Academic, tertiary children’s hospital. Patients: Patients who underwent CP surgery between 2000 and 2017. Exclusions included submucous CP or age at last contact under 3.9. Interventions: Cleft palate surgery, completed in either a single-stage or 2-stage repair. Main Outcome Measure(s): Rates of VPI diagnosis and speech surgery and total cleft surgeries; t tests, tests of proportion, and linear and logistic regression were performed. Total cleft-related surgeries were examined in a subset (n = 418) of patients with chart reviews. Results: A total of 1047 patients were included; 59.6% had 2-stage CP repair, 40.4% had single-stage repair. Approximately 32% of children with 2-stage CP repair were diagnosed with VPI, as opposed to 22% of single-stage patients ( P < .001). Children with 2-stage CP repair were 1.8 times as likely to be diagnosed with VPI ( P < .001). Speech surgery rates were similar across groups. Patients who had 2-stage repair received an average of 2.3 more cleft-related procedures, when excluding prosthesis management procedures. Conclusion: Our data show an increased risk of VPI diagnosis and increased surgical burden among patients receiving 2-stage CP repair.

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Measuring Patient-Reported Health-Related Quality of Life in Velopharyngeal Insufficiency: Reliability and Validity of the Brazilian Portuguese Version of the VELO Instrument

Cited by 15 publications

References 45 publications

Split Buccal Fat Flap in Modified Furlow Palatoplasty: Surgical Technique and Early Result

Split Buccal Fat Flap in Modified Furlow Palatoplasty: Surgical Technique and Early Result

Quality of Life in Patients With Velopharyngeal Insufficiency in West China

Increased Risk of Velopharyngeal Insufficiency in Patients Undergoing Staged Palate Repair

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