Measuring substantial reductions in functioning in patients with chronic fatigue syndrome

Jason, Leonard A.; Brown, Molly; Evans, Meredyth; Anderson, Valerie R.; Lerch, Athena; Brown, Abigail; Hunnell, Jessica; Porter, Nicole

doi:10.3109/09638288.2010.503256

Cited by 62 publications

(82 citation statements)

References 30 publications

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“…Jason, Evans, et al (2011) found that the MFI did identify all CFS cases, but these scales were not able to successfully identify those who did not have CFS. In addition, Jason, Brown, et al (2011) examined Reeves et al’s recommended use of selected subscales from the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) to measure disability. Notably, Jason, Brown, et al (2011) found that the Reeves et al recommended cutoff of less than or equal to 66.7 on the SF-36 Role-Emotional subscale would select the majority of those with chronic fatigue explained by psychiatric reasons as meeting the CFS disability criterion.…”

Section: Case Definitionsmentioning

confidence: 99%

“…In addition, Jason, Brown, et al (2011) examined Reeves et al’s recommended use of selected subscales from the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) to measure disability. Notably, Jason, Brown, et al (2011) found that the Reeves et al recommended cutoff of less than or equal to 66.7 on the SF-36 Role-Emotional subscale would select the majority of those with chronic fatigue explained by psychiatric reasons as meeting the CFS disability criterion. Furthermore, the area under the curve (AUC) for the Role-Emotional subscale was the worst among the eight SF-36 subscales for discriminating patients with CFS from controls (Jason, Brown, et al, 2011).…”

Section: Case Definitionsmentioning

confidence: 99%

See 1 more Smart Citation

Defining Essential Features of Myalgic Encephalomyelitis and Chronic Fatigue Syndrome

Jason¹,

Sunnquist²,

Brown³

et al. 2015

Journal of Human Behavior in the Social Environment

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Considerable debate surrounds the search for the defining features of patients with Myalgic Encephalomyelitis (ME) and chronic fatigue syndrome (CFS). Current case definitions were created through clinical consensus. Failure to operationalize these case definitions has led to considerable variability in the identification of patients. In addition, some case definitions (e.g., Fukuda et al., 1994) do not require cardinal symptoms of this illness, where as other case definitions do require core symptoms of this illness (Carruthers et al., 2003, 2011), and these latter case criteria appear to identify a more impaired group of patients. Criterion variance is most likely to occur when operationally explicit criteria do not exist for diagnostic categories (Spitzer, Endicott, & Robins, 1978), or when there are varying criteria for contrasting case definitions, which is an impediment to the research in this field. To deal with this problem, it is possible to differentiate those that meet more loosely defined criteria from those that are more narrowly and defined, thus differentiating CFS from ME. In order to progress the search for biological markers and effective treatments, essential features need to be operationalized and broadly used in order to increase the probability that individuals included in samples have the same underlying illness.

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Section: Case Definitionsmentioning

confidence: 99%

Section: Case Definitionsmentioning

confidence: 99%

Defining Essential Features of Myalgic Encephalomyelitis and Chronic Fatigue Syndrome

Jason¹,

Sunnquist²,

Brown³

et al. 2015

Journal of Human Behavior in the Social Environment

Self Cite

View full text Add to dashboard Cite

show abstract

“…In fact, Jason et al (2009) found that 38% of individuals who had primarily a Major Depressive Disorder (MDD) were misclassified as having CFS using the Reeves empiric CFS case definition (2005). In further support of this critique by Jason et al (2009), Jason et al (2011) found that the Role Emotional subscale had the worst sensitivity and specificity of all the SF-36 subscales using responses from both a community-based sample and a tertiary care sample.…”

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confidence: 91%

Measuring Substantial Reductions in Activity

Schafer

Evans

Jason

et al. 2015

Journal of Prevention & Intervention in the Community

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The case definitions for Myalgic Encephalomyelitis/chronic fatigue syndrome (ME/CFS), Myalgic Encephalomyelitis (ME), and chronic fatigue syndrome (CFS) each include a disability criterion requiring substantial reductions in activity in order to meet diagnostic criteria. Difficulties have been encountered in defining and operationalizing the substantial reduction disability criterion within these various illness definitions. The present study sought to relate measures of past and current activities in several domains including the SF-36, an objective measure of activity (e.g. actigraphy), a self-reported quality of life scale, and measures of symptom severity. Results of the study revealed that current work activities had the highest number of significant associations with domains such as the SF-36 subscales, actigraphy, and symptom scores. As an example, higher self-reported levels of current work activity were associated with better health. This suggests that current work related activities may provide a useful domain for helping operationalize the construct of substantial reductions in activity.

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“…Ware et al (2000) found that the mean for Role-Emotional for a clinical depression group was 38.9, indicating that almost all those with clinical depression would meet the CFS disability criterion, as they would be within the lower 25th percentile on this subscale. Jason et al (2010c) found that Role-Emotional had the lowest threshold for both identifying individuals with CFS and identifying others who did not have this illness. However, Vitality, Social Functioning and Role-Physical have the highest threshold.…”

Section: Substantial Reduction In Functioningmentioning

confidence: 99%

“…However, Vitality, Social Functioning and Role-Physical have the highest threshold. In a literature review, the Vitality, Social Functioning and RolePhysical subscales best discriminated those with CFS from controls (Jason et al, 2010c). The Vitality scale measures items that assess feeling full of pep and energy, as well as those that focus on feeling worn out or tired.…”

Section: Substantial Reduction In Functioningmentioning

confidence: 99%

The Development of a Revised Canadian Myalgic Encephalomyelitis Chronic Fatigue Syndrome Case Definition

Jason

Evans

Porter

et al. 2010

American Journal of Biochemistry and Biotechnology

140

150

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Problem statement: Several investigators have indicated that case definitions for Chronic Fatigue Syndrome (CFS) are characterized by vaguely worded criteria that lack operational definitions and guidelines. The most widely used CFS case definition is the Fukuda et al. criteria, which uses polythetic criteria (i.e., patients are only required to have four out of a possible eight symptoms). Yet two of these eight symptoms (post-exertional malaise and memory/concentration problems) are an essential feature of this illness and the Fukuda et al. criteria do not require that these symptoms be present among all patients. Significant methodological problems could occur if investigators in different settings recruit samples with different percentages of these core symptoms. In contrast, the Canadian clinical case definition does require specific ME/CFS symptoms such as post-exertional malaise and memory/concentration problems. The provision of operationally explicit, objective criteria on specific key symptoms might reduce criterion variance as a source of unreliability. In addition, the use of structured interview schedules will ensure that symptoms are assessed in a consistent way across settings. Conclusion/Recommendations: In this article, we specified explicit rules for determining whether critical symptoms meet ME/CFS criteria using a revised Canadian case definition and a questionnaire has been developed to assess core symptoms. It is hoped that these developments will lead to increased reliability of this revised Canadian case definition as well as more frequent use of these criteria by investigators.

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Measuring substantial reductions in functioning in patients with chronic fatigue syndrome

Cited by 62 publications

References 30 publications

Defining Essential Features of Myalgic Encephalomyelitis and Chronic Fatigue Syndrome

Defining Essential Features of Myalgic Encephalomyelitis and Chronic Fatigue Syndrome

Measuring Substantial Reductions in Activity

The Development of a Revised Canadian Myalgic Encephalomyelitis Chronic Fatigue Syndrome Case Definition

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