We present an analytical calculation of the leading three-loop radiative correction to the ρ-parameter in the Standard Model in the large Higgs mass limit. This correction, of order g 6 m 4H /M 4 W , is opposite in sign to the leading two-loop correction of order g 4 m 2 H /M 2 W . The two corrections cancel each other for a Higgs mass of approximately 480 GeV. The result shows that it is extremely unlikely that a strongly interacting Higgs sector could fit the data of electroweak precision measurements.