Measuring the orientation of segmented Deep Brain Stimulation leads using electroencephalography

Abstract

Segmented Deep Brain Stimulation (DBS) leads enable current steering in specific directions, but this comes with an increased level of programming complexity. Precise measurement of lead orientation is crucial for facilitating stimulation programming. Presently employed methods involve radiation technology posing inherent risks and limitations. Additionally, the potential rotation of leads post-implantation may require repeated measurements. To address these challenges, we propose an outpatient-friendly, radiation-free method using post-operative imaging-informed electroencephalography (EEG). The method was tested in an EEG phantom yielding maximal errors of under 10˚ with under 30s of data. It works with as few as 4 EEG electrodes with only a small error increase. Measurement variance was of the order of a few degrees, indicating that the method could reach this precision if all the sources of bias are removed. Thus, with optimised hardware, software and measurement protocol, the method is feasible for routine use in a clinical setting.