Warm spray is a novel thermal spray technique that allows the formation of dense and relatively pure Ti-6Al-4V coatings due to its capability to control the temperature of the propellant gas by diluting the combustion flame with an inert gas such as nitrogen. Recently, its combustion pressure has been increased from 1 to 4 MPa aiming to further increase particle velocity to over 1000 m/ s. Two series of coatings with combustion pressure of 1 and 4 MPa and various nitrogen flow rates were prepared in this study. Effects of combustion pressure and nitrogen flow rate on the microstructure and mechanical properties of the Ti-6Al-4V coatings were systematically studied. Miniature tensile specimens with a total length of about 9 mm were used for static tensile tests. It was found that the spray parameters affect both the porosity and oxygen content of the coatings significantly and had remarkable effects on their mechanical properties. High level of porosity in the Ti-6Al-4V coatings reduced the effective cross-sectional area of the mini-specimens and caused a drop in their tensile strength and Young's modulus. Subsequent heat treatments were found effective in significantly recovering the mechanical properties of the as-sprayed coatings.