Mechanical and thermal properties and cytotoxicity of Al₂O₃ nano particle-reinforced poly(ether-ether-ketone) for bone implants

Abstract

A novel preparation method for a PEEK/Al2O3 composite biomaterial for human bone implantation was proposed.

Evaluación de la citotoxicidad de fosfatos de calcio sintetizados a diferentes relaciones molares de Ca/P por la vía hidrotermal

“…Los valores de RGR% se clasificaron a partir de los valores de densidad óptica (DO) o absorbancia de acuerdo con la norma china GB/T 16886.5-2003, 0 y 1 representan la ausencia de citotoxicidad, mientras que 2, 3, 4 y 5 representan diferentes niveles de citotoxicidad. Se ha reportado que para RGR% ≥100 el nivel de citotoxicidad es 0, para 99 ≥ RGR% ≥75 es 1; 74 ≥ RGR% ≥50 es 2, 49 ≥ RGR% ≥25 es 3, 24≥ RGR% ≥1 es 4, y RGR% = 0 es 5 (Wei et al, 2019).…”

Effect of ionic liquids on thermomechanical properties of polyetheretherketone‐multiwalled carbon nanotubes nanocomposites

“…High-performance polyetheretherketone (PEEK) composites have attracted particular attention for the potential engineering applications, especially in the biomedical field for human bone replacement, because of their superior physicochemical characteristics, biocompatibility, and bone-like stiffness. 1,2 PEEK composites with the addition of multiwalled carbon nanotubes (MWCNTs) exhibited better efficacy in biomedical uses with reduced toxicity and improved mechanical and thermal stability due to their large surface area, low density, and higher tensile properties. 3,4 The PEEK/MWCNT composites have been manufactured by several methods to address the role of MWCNTs in PEEK, including solution mixing, 5 compounding and injection molding, 6 chemical modification of CNTs 7 and melt blending of PEEK with MWCNTs.…”

Synergistic effect of carbon nanotubes and nano-hydroxyapatite on mechanical properties of polyetheretherketone based hybrid nanocomposites

“…9,16 The mechanical properties of PEEK are weaker than that of human cortical bones, as the elastic modulus of PEEK is around 3.5 GPa while that of the cortical bone lies within the range of 6 to 30 GPa. 17 The poor bioactivity and mechanical properties restrict the use of PEEK in load-bearing orthopedic implants such as the knee, hip, and other joint implants. 9 Other applications of PEEK composites are prevalent in products such as bearing, pumps, piston parts, compressor valves, electric insulation.…”