Hybrid composite specimens of the fracture fixation device were made by the hot pressing technique. The weight fraction of nanoparticles and Types are most significant on the properties. The compression strength, hardness, and density increased with increasing nanoparticle weight fraction.Bone plates are essential for bone fracture healing because they modify the biomechanical microenvironment at the fracture site to provide the necessary mechanical fixation for fracture fragments. This paper addresses the use of composite bone plates in healing long-bone fractures such as transverse fractures of the femur. However, stress shielding in the bone due to metal plates can be reduced by designing implants with Bio-composites that involve Ultra high molecular polyethylene reinforced (UHM WPE) with Nano hydroxyapatite (n-HA) and Nano titanium dioxide (n-TiO2) particles at different weight fraction (0,1.5,2.5,3.5and 4. 5%) and 5% of carbon and Kevlar fibers. FRIT spectrum was used to identify the incorporation between the matrix and Nano particles, and the shifting in main peaks confirmed the good cross-linking within the composite structure. The specimens thus prepared were subjected to a compression test, hardness test, and density. The results indicated that UHM WPE+4.5%n-HA+CF hybrid biocomposite has the highest compressive strength and hardness properties. In contrast, UHM WPE+4.5%TiO2+CF has the highest density , which increased with increasing percentages of weight fraction of Nano-particles, where the compression strength 53 M Pa, hardness property ranges 65.6 shore D, and density 1.09 (g/cm 3 ). According to the current study's findings, it is possible to create biocomposites as internal fixation device with improved performance by placing different fiber reinforcements.