Numerical studies were conducted to investigate the optimum curvature of a carbon fibrereinforced polymer (CFRP) panel that would provide an improved blast resistance. A dynamic finite-element (FE) model that incorporates fluid-structure interaction was developed to evaluate the response of these panels to blast in commercial finite-element software ABAQUS/Explicit. Previously reported experimental data by authors were utilised to validate a FE model, where a shock-tube apparatus was utilized to apply a controlled shock loading to quasi-isotropic composite panels with different radii of curvature. A threedimensional digital image correlation (DIC) technique coupled with high-speed photography was employed to measure out-of-plane deflections and velocities, as well as in-plane strains at the back face of panels. Macroscopic post-mortem analysis was performed to compare the deformation in these panels. The numerical results were compared to the experimental data and demonstrated a good agreement. The validated FE model was further used to predict the optimal curvature of CFRP panel with the aim to improve its blast-mitigation characteristics.