Mechanical Circulatory Support as a Bridge to Heart Transplantation: What Remains? Long-term Emotional Sequelae in Patients and Spouses

Bunzel, Brigitta; Laederach‐Hofmann, Kurt; Wieselthaler, Georg; Roethy, Wilfried; Wolner, Ernst

doi:10.1016/j.healun.2007.01.025

Cited by 79 publications

(70 citation statements)

References 23 publications

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“…38 Patients receiving therapy via pulsatile and continuous-flow devices were not significantly different on symptoms of anxiety, depression, and posttraumatic stress disorder. 19 The cross-sectional study of Meyer et al 34 found no significant differences in domain scores between 2 continuous-flow systems: the centrifugal-flow pump Heartmate II and the axial-flow pump HVAD.…”

Section: Pros In Studies On Continuous-flow Devicesmentioning

confidence: 97%

“…From each cohort, only the most recent article was included (ie, articles with the most optimal study design and largest sample size), except for 2 extra articles that compared 2 groups of patients receiving LVAD therapy with 2 different devices. 12,18,19,[25][26][27] Hence, the current review is based on 16 studies (Figure).…”

Section: Literature Searchmentioning

confidence: 99%

“…18,25,27,36 -38 The baseline assessment was performed within 1 month after LVAD implantation in the prospective studies. The retrospective study 35 assessed PROs at 12 months after LVAD implantation, and the cross-sectional studies 19,35 included patients ranging from 2 to 135 months after LVAD implantation. Two studies 19,36 …”

Section: Literature Overviewmentioning

confidence: 99%

“…Patients supported by pulsatile devices showed relatively high mean depression scores just after LVAD implantation. 26,29,31 The retrospective study 19 of Bunzel et al 20 found no significant difference in depression scores between patients receiving therapy via pulsatile vs continuous-flow devices; these patients might be more vulnerable to psychological distress, based on the higher rate of complications and the characteristics of the device (eg, short durability, large size, noise, and large batteries). Hence, these differences in findings could well be explained by sample size limitations, differences in subtype of devices, and the time of collecting data.…”

Section: Summary Of the Findingsmentioning

confidence: 99%

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Patient-Reported Outcomes in Left Ventricular Assist Device Therapy

Brouwers

Denollet

Jonge

et al. 2011

Circ: Heart Failure

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Patient-reported outcomes in left ventricular assist device therapyBrouwers, C.J.; Denollet, J.; de Jonge, N.; Caliskan, K.; Kealy, J.; Pedersen, S.S. General rightsCopyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights.-Users may download and print one copy of any publication from the public portal for the purpose of private study or research -You may not further distribute the material or use it for any profit-making activity or commercial gain -You may freely distribute the URL identifying the publication in the public portal Take down policyIf you believe that this document breaches copyright, please contact us providing details, and we will remove access to the work immediately and investigate your claim. Background-Technological advancements of left ventricular assist devices (LVAD) have created today's potential for extending the lives of patients with end-stage heart failure. Few studies have examined the effect of LVAD therapy on patient-reported outcomes (PROs), such as health status, quality of life, and anxiety/depression, despite poor PROs predicting mortality and rehospitalization in patients with heart failure. In this systematic review, we provide an overview of available evidence on the impact of LVAD therapy on PROs and discuss recommendations for clinical research and practice. Methods and Results-A systematic literature search identified 16 quantitative studies with a sample size Ն10 (meanϮSD ageϭ50.1Ϯ12.6 years) that examined the impact of LVAD therapy on PROs using a quantitative approach. Initial evidence suggests an improvement in health status, anxiety, and depression in the first few months after LVAD implantation. However, PRO scores of patients receiving LVAD therapy are still lower for physical, social, and emotional functioning compared with transplant recipients. These studies had several methodological shortcomings, including the use of relatively small sample sizes, and only a paucity of studies focused on anxiety and depression. Conclusions-There is a paucity of studies on the patient perspective of LVAD therapy. To advance the field of LVAD research and to optimize the care of an increasingly growing population of patients receiving LVAD therapy, more well-designed large-scale studies are needed to further elucidate the impact of LVAD therapy on PROs. (Circ Heart Fail. 2011;4:714-723.)Key Words: left ventricular assist device Ⅲ patient-reported outcomes Ⅲ quality of life Ⅲ review

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Section: Pros In Studies On Continuous-flow Devicesmentioning

confidence: 97%

Section: Literature Searchmentioning

confidence: 99%

Section: Literature Overviewmentioning

confidence: 99%

Section: Summary Of the Findingsmentioning

confidence: 99%

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Patient-Reported Outcomes in Left Ventricular Assist Device Therapy

Brouwers

Denollet

Jonge

et al. 2011

Circ: Heart Failure

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“…However, research of the psychologic aspects of VAD therapy has been limited to date (84)(85)(86). Surprisingly, post-traumatic stress disorder (PTSD) has not been described in patients who have undergone VAD implantation but rather in their spouses (87). In one particular survey, 26% of spouses, but none of the patients, met criteria for PTSD.…”

Section: Complicationsmentioning

confidence: 99%

Ventricular Assist Devices and Total Artificial Hearts

Blitz

Fang

2009

Device Therapy in Heart Failure

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Cardiac Disease‐Induced Post‐traumatic Stress Symptoms (CDI‐PTSS) Among Patients' Partners

et al. 2016

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It is well established that a patient's partner can be deeply affected by the traumatizing nature of the patient's illness. Yet, no study to date has focused on post-traumatic stress symptoms (PTSS) among partners of patients coping with an acute coronary syndrome (ACS). The current study's main aims were to address this gap and to evaluate cardiac disease-induced (CDI) PTSS prevalence in partners of patients who experienced ACS. Patients who experienced ACS and their partners were interviewed by telephone 2 to 6 months after patients' hospitalization. All patients and partners were screened for CDI-PTSS. Demographic and medical variables as well as partners' level of exposure to the cardiac event were assessed. Prevalence of CDI-PTSS was higher among partners than among patients. Partners' number of CDI-PTSS was not significantly associated with patients' number of CDI-PTSS or with any of the other explanatory factors measured, except for education level. The preliminary results that arose from the current study point to the vast number of individuals who must act as caregivers for their ill partners while having to cope with their own PTSS. Much effort should be channelled into integrating partners into cardiac recovery programmes. Copyright © 2016 John Wiley & Sons, Ltd.

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Mechanical Circulatory Support as a Bridge to Heart Transplantation: What Remains? Long-term Emotional Sequelae in Patients and Spouses

Cited by 79 publications

References 23 publications

Patient-Reported Outcomes in Left Ventricular Assist Device Therapy

Patient-Reported Outcomes in Left Ventricular Assist Device Therapy

Ventricular Assist Devices and Total Artificial Hearts

Cardiac Disease‐Induced Post‐traumatic Stress Symptoms (CDI‐PTSS) Among Patients' Partners

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