Mechanical dry particle coating on cohesive pharmaceutical powders for improving flowability - A review

Sharma, Rahul; Setia, Gautam

doi:10.1016/j.powtec.2019.08.009

Cited by 60 publications

(42 citation statements)

References 95 publications

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“…There were two main flow patterns of the steel particles in the high-pressure tank during the feeding process [28][29][30][31]. One was the overall flow, and all the steel particles flowed at the same time during the feeding.…”

Section: Resultsmentioning

confidence: 99%

Investigation into the Mechanism of the Steel Particle Feeding Process: A Numerical and Experimental Study

Xing

Wang³

et al. 2021

Geofluids

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The particle feeding system is a prerequisite for the realization of particle impact drilling technology. Because of the high density, the storage and flow of the steel particle are different from those of the other nonviscous particles. The differential equation of the particle movement was built with the liquid bridge force model and the discrete element method. The dynamic movement process and the distribution state of particles in the high-pressure tank were analyzed. For 1 mm steel particles, the mass flow rate decreased with the increase in water content. For 2 mm and 3 mm steel particles, the water content of 15% and 20% was the dividing point of the mass flow rate from increasing to decreasing. When the water content was 10% and 20%, the mass flow rate increased with the steel particle size. But when the water content was 30% and 40%, the mass flow rate decreased with the steel particle size. The study of the control mechanism of the uniformity and stability of particles showed that the funnel flow was the major reason causing the instability and blocking of the feeding process. This research results can provide a basis for the further improvement of the differential pressure feeding system.

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Section: Resultsmentioning

confidence: 99%

Investigation into the Mechanism of the Steel Particle Feeding Process: A Numerical and Experimental Study

Xing

Wang³

et al. 2021

Geofluids

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“…Recently, many routes for the dry coating of particles were realized in order to produce advanced materials by coating the surface of larger core (host) particles with fine shell (guest) particles through mechanical forces [83,84]. Among the various routes, mechanofusion (MF) provides an exceptional solution [85] by attaining a considerable capacity to produce composite powders with the desired tailor-made properties for advanced MMCs [42,85,86].…”

Section: Flake Powder Metallurgy High-shear Pre-dispersion and Ssbm (Fpm-hspd/ssbm)mentioning

confidence: 99%

Progress of Flake Powder Metallurgy Research

Sadeghi

Cavaliere

2021

Metals

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This paper reviewed several recent progresses of the new powder metallurgy technology known as flake powder metallurgy (FPM) including different processing routes, conventional FPM (C-FPM), slurry blending (SB), shift-speed ball milling (SSBM), and high-shear pre-dispersion and SSBM (HSPD/SSBM). The name of FPM was derived from the use of flake metal powders obtained by low-speed ball milling (LSBM) from spherical powder. In this case, the uniformity of reinforcement distribution leads to increased strength and ductility. Powder is the basic unit in PM, especially advanced PM, and its control is key to various new PM technologies. The FPM is a typical method for finely controlling the powder shape through low-energy ball milling (LEBM) to realize the preparation of advanced material structures. The present paper represents a review of the main results of research on FPM and indicates the potential for future studies devoted to the optimization of this processing route.

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“…Mechanofusion by Hosokawa Micron, Hybrydizer by Nara Machinery or Theta Composer by Tokuju Company. Background of dry coating as well as different methods and devices have been previously widely described in the literature, e. g. by [44,45] and the reader is referred to this literature.…”

Section: Improvement Of Powder Flowabilitymentioning

confidence: 99%

Studies on Moisture Effects on Powder Flow and Mechanochemical Improvement of Powder Flowability

Opaliński¹,

Chutkowski²,

Mateusz³

et al. 2021

Adv. Sci. Technol. Res. J.

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Recent findings on some unsolved powder rheology problems and new challenges regarding mechanochemical powder processing and flow modelling are presented. There is remarkable difference in rheology when processing moist powders in static or dynamic conditions. Despite of regular trends of shear stress changes with humidity found in the both cases, some exceptions revealed the significant impact of particles size and their hygroscopic nature as example. Mechanochemical methods of high-energy interactive mixing of highly cohesive powders doped with nano-sized solid admixture enabled their flowability to be improved considerably. Using statistical approach, more general routine is proposed that allow the optimal mixing parameters to be reliably predicted with limited number of experiments needed. Ability to flow of some hygroscopic powders was examined with DEM method and extreme sensitivity of model output to input particle properties was found. The common DEM routine towards powder flow prediction is therefore suggested to be replaced with approach featuring in using DEM method to identify some unknown powder flow factors.

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Mechanical dry particle coating on cohesive pharmaceutical powders for improving flowability - A review

Cited by 60 publications

References 95 publications

Investigation into the Mechanism of the Steel Particle Feeding Process: A Numerical and Experimental Study

Investigation into the Mechanism of the Steel Particle Feeding Process: A Numerical and Experimental Study

Progress of Flake Powder Metallurgy Research

Studies on Moisture Effects on Powder Flow and Mechanochemical Improvement of Powder Flowability

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