2005
DOI: 10.1016/j.jacc.2004.11.074
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Mechanical Dyssynchrony Assessed by Tissue Doppler Imaging Is a Powerful Predictor of Mortality in Congestive Heart Failure With Normal QRS Duration

Abstract: Myocardial dyssynchrony assessed by TDI is a powerful predictor of clinical events in CHF with normal QRS.

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Cited by 143 publications
(101 citation statements)
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“…In this group of patients, the loss of LV synchronous contraction was related to impaired LV systolic function and poor hemodynamic status, which is an indicator of a poor outcome (11,24). Cho et al (25,26) demonstrated that mechanical dyssynchrony was a powerful predictor of mortality or cardiac events in heart failure patients with normal and wide QRS. Penicka et al (11), Fauchier et al (27), and Bader et al (10) reported that LV dyssynchrony was prognostic of cardiac endpoints.…”
Section: Discussionmentioning
confidence: 90%
See 1 more Smart Citation
“…In this group of patients, the loss of LV synchronous contraction was related to impaired LV systolic function and poor hemodynamic status, which is an indicator of a poor outcome (11,24). Cho et al (25,26) demonstrated that mechanical dyssynchrony was a powerful predictor of mortality or cardiac events in heart failure patients with normal and wide QRS. Penicka et al (11), Fauchier et al (27), and Bader et al (10) reported that LV dyssynchrony was prognostic of cardiac endpoints.…”
Section: Discussionmentioning
confidence: 90%
“…(26) Inferior MI (%) (n) 41 (18) Diabetes mellitus (%) (n) 27 (12) Cigarette smoking (%) (n) 56 (25) Family history (%) (n) 16 (7) Hypertension (%) (n) 68 (29) Hyperlipidemia (%) (n) 21 (9) Time of acceptance (hour)(min-max duration) 5.1±1. anterior AMI group, the Ts values of the basal-septal segment, basal-anterior segment, mid-anterior segment were significantly decreased in post-PCI measurements (p<0.01).…”
Section: Diagnosismentioning
confidence: 99%
“…Cho et al 6 assessed dyssynchrony in 106 patients with heart failure and found that dyssynchrony was a strong predictor of severe clinical events. Similarly, Bader et al 4 , describing a group of 104 patients, showed that the presence of intraventricular dyssynchrony is a determinant factor of adverse cardiac events, regardless of ejection fraction and QRS 4 .…”
Section: Discussionmentioning
confidence: 99%
“…Recently, Rassi et al 3 published a risk score with good prognostic accuracy, taking into account gender, low voltage on electrocardiogram, cardiomegaly on chest x-ray, non-sustained ventricular tachycardia, functional class and reduced ejection fraction on the echocardiogram. In addition to quantifying the degree of ventricular dysfunction, the echocardiogram has recently emerged as a tool to determine the presence of ventricular dyssynchrony, which is related to a worse prognosis in cardiomyopathies of other etiologies [4][5][6] . The prognostic value of ventricular dyssynchrony in patients with Chagas' cardiomyopathy is not known.…”
Section: Introductionmentioning
confidence: 99%
“…6,7 In the presence of abnormal substrate, several studies have showed increased risk of adverse cardiovascular outcomes in patients with dyssynchrony but data on arrhythmic events are less convincing. [8][9][10][11] A sub-study of MADIT-CRT showed no difference in the occurrence of ventricular arrhythmias in patients undergoing CRT implantation with or without baseline dyssynchrony. 10 In REVERSE trial there was no difference in occurrence of ventricular arrhythmias in patients with CRT ON vs CRT OFF implying resynchronization had little impact on occurrence of ventricular arrhythmias.…”
Section: See Related Article Pp 555-569mentioning
confidence: 99%