Mechanical or bioprosthetic valves in the elderly: a 20-year comparison

Sidhu, Pushpinder; O'Kane, Hugh; Ali, Niaz; Gladstone, Dennis; Sarsam, Mazin A.I.; Campalani, Gianfranco; MacGowan, Simon W.

doi:10.1016/s0003-4975(01)02522-x

Cited by 60 publications

(29 citation statements)

References 6 publications

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“…In contrast, the main advantage of bioprosthetic valves is the avoidance of anticoagulation; however, their durability is limited. Several trials showed that patient outcome after AVR is independent of the type of implanted prosthesis (mechanical versus biological) [22,23]. Significant differences are found only regarding the rate of major hemorrhage; these are more common in patients with mechanical valves: the incidence ranges from 1 to 2% per patient-year.…”

Section: Aortic Valve Replacementmentioning

confidence: 99%

Cardiac Surgery in Elderly Patients: What Is the Evidence?

Matt¹,

Bernet²,

Grapow³

et al. 2004

Heart Drug

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Coronary artery bypass surgery and aortic valve replacement can be performed with an acceptable operative risk in the elderly: the 30-day mortality ranges from 2 to 8%. However, the indication for surgery should be individualized based on the patient’s personal situation, physical condition, mental status, compliance and the comorbidities. The primary goal of open heart surgery in old patients should be the improvement in quality of life, and the secondary goal, the prognosis. Interestingly the mid- and long-term survival after cardiac surgery in the elderly corresponds to an age-adjusted population without heart disease.

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Section: Aortic Valve Replacementmentioning

confidence: 99%

Cardiac Surgery in Elderly Patients: What Is the Evidence?

Matt¹,

Bernet²,

Grapow³

et al. 2004

Heart Drug

View full text Add to dashboard Cite

show abstract

“…group of patients have been performed with an acceptable morbidity and mortality [2][3][4][5][6][7][8] . Long term clinical follow up of these patients has clearly demonstrated that bioprosthesis are the valve substitutes of choice in this group of patients 1,[3][4][5][6][7][8][9][10][11] .…”

mentioning

confidence: 99%

“…Long term clinical follow up of these patients has clearly demonstrated that bioprosthesis are the valve substitutes of choice in this group of patients 1,[3][4][5][6][7][8][9][10][11] . However there is lack of information on patients from India undergoing bioprosthetic valve replacement.…”

mentioning

confidence: 99%

Tissue heart valve implantation in India; Indications, results and impact on quality of life

Talwar

Sharma

Kumar

2008

Indian J Thorac Cardiovasc Surg

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“…But all of them highlight the higher incidence of anticoagulant related haemorrhage in the mechanical valve group 2,4,5 . The incidence of thromboembolism, paravalvular leaks, infective endocarditis, structural dysfunction and valve related deaths were not significantly different in either group 4,5 . Avoidance of the risk of anticoagulant related haemorrhage is a major consideration apart from durability, in the choice of bioprosthesis in elderly 5 .…”

Section: Discussionmentioning

confidence: 77%

“…Our patient group comprises of predominantly economically backward individuals living in villages with no immediate access to such facilities. Avoiding anticoagulation is therefore 2,4 . But all of them highlight the higher incidence of anticoagulant related haemorrhage in the mechanical valve group 2,4,5 .…”

Section: Discussionmentioning

confidence: 99%