Bio-based building products are considered key in our future socio-economic environment, since they are a very relevant nature-based solution (NbS) to climate change. The statement of President von der Leyen (European commission) to turn the construction sector into a carbon sink is critical in this respect: bio-based materials should be used on a larger and more targeted scale in the future. The long-term use of materials is therefore very important since we need to improve the lifespan of renewable materials to increase its carbon sink potential. Hence wood is increasingly considered as a main building material. Service life aspects are critical in relation to the EU Construction Products Regulation (CPR). Traditional treatments to protect against fungal decay and the impact of fire are not always performing adequately and often environmental impact has been an important consideration. The option to enhance wood properties using innovative technologies can be combined with better definition of the expectations and requirements. Besides focusing on combined innovative treatments of the wood matrix, also envelope treatments similar to the use of coatings can be envisaged. This all should lead to an increased use of timber and engineered wood products for green building. This paper mainly focusses on the increased use and high potential of CLT (Cross Laminated Timber) and options to use hardwoods and modified wood (like TMT) in relation to moisture dynamics to come to fit-for-purpose material properties even under more hazardous circumstances.