Mechanical Properties Analysis of Gelatin/Carboxymethylcellulose Scaffolds

Wiwatwongwana, Fasai; Chaijit, Seksan

doi:10.18178/ijmmm.2019.7.3.447

Cited by 3 publications

(3 citation statements)

References 17 publications

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“…Wiwatwongwana and Chaijit [24] proposed using the freeze-drying method to create a gelatin-CMC scaffold with various ratios. Using universal testing equipment, a compressive test was done to characterize the scaffold mechanically.…”

Section: Dong and Duanmentioning

confidence: 99%

“…As a result, a basic hyperelastic material model, especially the neo-Hookean model, can describe the constitutive behavior of the scaffold. Curve fitting from a homogeneity test or uniaxial compression test can determine scaffold construction parameters [24,25]. The hyperelastic model with a neo-Hookean model is presented in this study, along with a compressive modulus for researching shear modulus with a neo-Hookean model.…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of polycaprolactone/carboxymethylcellulose scaffolds using hyperelastic model

2022

IJATEE

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Tissue engineering is an interesting field. The tissue engineering scaffold allows the delivery of cells and growth factors to the damaged part of the body to allow for the regeneration of tissue. This work aimed to evaluate polycaprolactone (PCL) blended with carboxymethylcellulose (CMC) composite scaffolds. The porous scaffolds were created using the salt leaching process. An experimental technique was used to characterize the mechanical characteristics of the scaffolds.We evaluated the modeling by describing the stress-strain behavior of the scaffolds using the neo-Hookean model. The shear modulus of the polycaprolactone scaffold containing 2, 11, 15.5, and 20% CMC was 0.074, 0.037, 0.034, and 0.085 megapascal (MPa), respectively. A scaffold with a PCL/CMC ratio of 93.5/6.5 had the highest average shear modulus of 0.245 MPa when compared to other mixed scaffolds. There was a significant difference when compared to a pure polycaprolactone scaffold. The result could provide excellent conditions for creating scaffolds for use in cell transplantation and culture.

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Section: Dong and Duanmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Evaluation of polycaprolactone/carboxymethylcellulose scaffolds using hyperelastic model

2022

IJATEE

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“…The fabrication procedures of gelatin/CMC scaffold were the same as previous research [16]. Type A gelatin was purchased from BIO BASIC INC, Canada.…”

Section: Materials Fabricationmentioning

confidence: 99%

Mechanical Properties Analysis of Scaffold Material Using Nonlinear Least Squares Fitting by Hyperelastic Model

Wiwatwongwana¹,

Promma²

2020

IJMMM

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Nowadays, the number of chronic wounds is on the rise. Wounds can caused by many problems such as disease, burn, ulceration, trauma and accident. Tissue engineering aims to produce porous scaffold biomaterials to regenerate damaged tissues to growth of new tissue. This research, gelatin was blended with Carboxymethylcellulose (CMC) in various conditions and fabricated to porous structure by using freezedrying method. All scaffolds were strengthen their structure by dehydrothermal crosslinking. Normally, the scaffold behavior is likely to be a foam-like hyperelastic material. Therefore, this research was selected Blatz-Ko model to describe the material behavior that acts as a foam rubber. This model could apply with both cases of compressible and incompressible material. The mechanical characterization of the scaffold was investigated by compressive test using universal testing machine (UTM). The experimental data obtained from the UTM was used to plot the stress-strain curve. The initial shear modulus of the material was identified by function derived from Blatz-Ko hyperelastic model using non-linear curve fitting method. The result revealed that Blatz-Ko model could fit curve at approximately 7% strain which was suitable for infinitesimal strain theory. The dehydrothermal treated scaffold with 90:10 gelatin/CMC ratio showed the highest shear modulus of 10.47±1.21 kPa. The structural collapse occurred in 60:40 gelatin/CMC scaffold. The physical characterization was done by using scanning electron microscopy (SEM) to investigate surface morphology and pore size of scaffolds. The results showed the appropriate pore size of the scaffold with average pore size of 117 µm to 197 µm. The 90:10 gelatin/CMC scaffold showed the biggest pore size.

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Effect of glutraldehyde and halloysite on gelatin-carboxymethyl cellulose gel formed via phase separation: Potential application in removal of methylene blue from waste water

Firdaus

Tiwari

Arfin

2022

Carbohydrate Polymer Technologies and Applications

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Mechanical Properties Analysis of Gelatin/Carboxymethylcellulose Scaffolds

Cited by 3 publications

References 17 publications

Evaluation of polycaprolactone/carboxymethylcellulose scaffolds using hyperelastic model

Evaluation of polycaprolactone/carboxymethylcellulose scaffolds using hyperelastic model

Mechanical Properties Analysis of Scaffold Material Using Nonlinear Least Squares Fitting by Hyperelastic Model

Effect of glutraldehyde and halloysite on gelatin-carboxymethyl cellulose gel formed via phase separation: Potential application in removal of methylene blue from waste water

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