Mechanical properties and apatite-forming ability of PMMA bone cements

Rentería-Zamarrón, D.; Cortés-Hernández, Dora A.; Bretado-Aragón, Luis A.; Ortega-Lara, Wendy

doi:10.1016/j.matdes.2008.11.024

Cited by 28 publications

(22 citation statements)

References 14 publications

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“…In addition, hydroxyapatite composite implant materials have become a promising alternative to acrylic cement in stabilizing fractures and cancellous screw fixation in elderly and osteoporotic patients [7,8]. The first use of poly(methyl methacrylate) as a dental device was for the fabrication of complete denture bases [9,10]. Although numerous new alloplastic materials show promise, the versatility and reliability of PMMA cause it to remain a popular and frequently used material [11,12].…”

Section: Introductionmentioning

confidence: 99%

The use of different alumina fillers for improvement of the mechanical properties of hybrid PMMA composites

et al. 2015

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Alumina fillers having different morphologies were used for reinforcement of PMMA-based composite materials. The employed fillers had the same chemical composition but morphologically were spherical nanoparticles, whiskers and an electrospun product that was composed of micro-sized mostly spherical particles and nanofibers. The electrospun product was obtained from aluminum chloride hydroxide/PVA/water solution. All fillers were added without surface treatment and mechanical characteristics of obtained composites were determined using dynamic mechanical analysis (DMA) and nanoindentation. From the nanoindentation results, the reduced elastic modulus for the obtained specimens using 3 wt.% of electrospun product was 134% of the one obtained with the polymer alone and the hardness was improved to 157.8% compared to the polymer without any additive. DMA shows that the storage modulus at room temperature was twice that of the polymer alone.

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Section: Introductionmentioning

confidence: 99%

The use of different alumina fillers for improvement of the mechanical properties of hybrid PMMA composites

et al. 2015

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“…In fact, by incorporation of more than 20 wt.% BAGH, the comparatively weak interfacial polymer/ BAGH interactions as well as agglomeration of the BAGH throughout the synthesis of bone cement may result in reducing elongation. 8,16,27 The incorporation of BAGH particles into the cement matrix as a reinforcement phase acts as a grain boundary to hinder crack growth, thus increasing the mechanical properties. Because of this, a circumferential compressive stress was formed in the matrix in the vicinity of the BAGH particles.…”

Section: Mechanical Propertiesmentioning

confidence: 99%

“…However, PMMA suffers from a number of drawbacks which should be addressed before it is considered for orthopedic applications. 8 In this context, addition of bioceramics to PMMA bone cements was investigated by several researchers in order to obtain bioactive bone cement. Nowadays, polymer blends have attracted considerable attention because of their ability to amalgamate the characteristics of the two components and overcome the drawbacks of individual polymers.…”

Section: Introductionmentioning

confidence: 99%

Apatite‐forming ability, cytocompatibility, and mechanical properties enhancement of poly methyl methacrylate‐based bone cements by incorporating of baghdadite nanoparticles

Pahlevanzadeh

Bakhsheshi-Rad

Ismail

et al. 2019

Int J Applied Ceramic Tech

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Bone cement synthesis through combination of polymers and bioceramics leads to the enhancement of mechanical and biological performances required for osteogenic properties and apatite‐formation ability with the aim of new bone growth. The purpose of the present study is to characterize a novel poly methyl methacrylate–poly caprolactone (PCL) bone cement containing baghdadite (BAGH) for orthopedic applications. Considerable enhancement in the mechanical properties was found in the cement containing BAGH compared to the cement without BAGH. Noticeably, favorable bioactivity was found in the bone cement containing BAGH, while the cement without BAGH presented poor bioactivity. The MTT assay illustrated that the MG63 osteoblasts' viability was noticeably improved by incorporation of BAGH into the cement. In addition, higher cell attachment and spreading were observed in the cement containing BAGH compared to the cement without BAGH. Hence, the synergistic effects of the cement containing BAGH including high mechanical properties, good bioactivity, and desirable cytocompatibility make it an attractive candidate for filling bone defects in orthopedic surgeries.

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“…PMMA is well tolerated in the body, but cannot bond to bone directly. Thus, many types of bio-active bone cements have been developed to overcome this problem [62,63]. The bio-active cements impart superior adhesion to the bone and provide acceptable mechanical properties.…”

Section: Biomaterials Considerationsmentioning

confidence: 99%

Aseptic loosening of femoral components – Materials engineering and design considerations

et al. 2013

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a b s t r a c tAseptic loosening is one of the main reasons for the revision of a total knee replacement (TKR). The design of the key component of a TKR, the femoral component, is particularly problematic because its failure can be the result of different causes. This makes the development of new biomaterials for use in the femoral component a challenging task. This paper focuses on the engineering design aspects in order to understand the limitations of current materials and design deficiencies. The paper describes the introduction of a new biomaterial for a femoral component and justifies the recommendation to use multi-functional materials as a possible solution to aseptic loosening. The potential advantages of applying functionally graded biomaterials (FGBMs) in prosthetic femur are explained by reducing the leading causes of failure including wear, micro-motion and stress-shielding effect. The ideas presented in this paper can be used as the basis for further research on the feasibility and advantages of applying FGBM in other superior implant designs.

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Mechanical properties and apatite-forming ability of PMMA bone cements

Cited by 28 publications

References 14 publications

The use of different alumina fillers for improvement of the mechanical properties of hybrid PMMA composites

The use of different alumina fillers for improvement of the mechanical properties of hybrid PMMA composites

Apatite‐forming ability, cytocompatibility, and mechanical properties enhancement of poly methyl methacrylate‐based bone cements by incorporating of baghdadite nanoparticles

Aseptic loosening of femoral components – Materials engineering and design considerations

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