Mechanical properties and sustainable bacterial resistance effect of strontium-modified phosphate-based glass microfiller in dental composite resins

Abstract

Dental composite resins are widely used in dental restorations. However, their clinical application is limited by the occurrence of secondary caries. Strontium-modified phosphate-based glass (Sr-PBG) is a material known to have a sustainable bacterial resistance effect. The mechanical properties (in particular, flexural strength, modulus of elasticity, and hardness) of dental materials determine their function. Therefore, this study aimed to investigate the mechanical and ion-releasing properties as well as the sustainable bacterial resistance effect of bioactive resin composites containing Sr-PBG. The data were analyzed by ANOVA and Tuckey’s tests (p < 0.05). We incorporated a Sr-PBG microfiller at 3, 6, and 9 wt.% concentrations into a commercially available composite resin and investigated the mechanical properties (flexural strength, elastic modulus, and micro hardness), ion release characteristics, and color of the resultant resins. In addition, we examined the antibacterial effects of the composite resins against Streptococcus mutans (S. mutans). The mechanical properties of the Sr-PBG groups differed only slightly from those of the control group (p > 0.05). However, the optical density at 600 nm of S. mutans incubated on the experimental group was significantly lower compared to that observed with the control (p < 0.05) both before and after thermocycling between 5 and 55 ℃ for 850 cycles (dwell time: 45 s). Therefore, strontium-modified resin materials exhibited a sustainable bacterial resistance effect in vitro while maintaining some of the mechanical properties of ordinary acrylic resins.

In vitro antifungal and physicochemical properties of polymerized acrylic resin containing strontium-modified phosphate-based glass

“…This study evaluated the in vitro antimicrobial, surface, and physicochemical properties of a newly developed material for removable orthodontic retainers. Despite the demonstrated biocompatibility and safety of similar materials in previous studies [ 39 ], the long-term effects and stability of strontium-modified phosphate-based glass in orthodontic applications are less well understood. A major limitation of our in vitro approach is the exclusion of natural factors such as saliva, which could potentially alter the properties of the material and its antimicrobial efficacy.…”

Antibacterial Agents Used in Modifications of Dental Resin Composites: A Systematic Review

“…A sustained in vitro bacterial resistance effect was achieved [57] Nanoparticle-modified MC with a nano-antibacterial inorganic filler (NIF) containing a quaternary ammonium salt…”

“…Go et al [57] decided to use strontium-modified phosphate glass (Sr-PBG) as a matrix filler. The filler was incorporated at three concentrations-3, 6, and 9 wt%-into a commercial composite (Filtek Z350XT, 3M ESPE).…”

Performance Assessment of Three Similar Dental Restorative Composite Materials via Raman Spectroscopy Supported by Complementary Methods Such as Hardness and Density Measurements

“…), but complete this list with their sustainable bacterial resistance. A good example is the use of strontium phosphate glass microfiller, which can inhibit the microbial growth of S. mutans while maintaining the mechanical properties [ 17 ]. A major drawback is, however, the release of Ca, P, and Sr in the oral environment (its release increases with the increase in the strontium phosphate concentration in the filler).…”