Mechanical Properties of Freestanding Polyelectrolyte Capsules: a Quantitative Approach Based on Shell Theory

Determination of the elastic properties of single microcapsules using micromanipulation and finite element modeling

“…A second limitation of these analytical models is that they do not consider bending effects in the wall, which implies that the wall thickness (h) is very small in comparison with the radius (r) of the capsule, for example as in polyeletrolyte microcapsules with h/r $ 0.3% (Elsner et al, 2006). The omission of bending effects, however, is not significant when the relevant compression data is obtained at high deformations (Lulevich et al, 2004).…”

“…The total force of compression is commonly split between a bending and a stretching membrane term, the former is linear in the fractional deformation e, while the latter is cubic in e (Lulevich et al, 2004;Fery et al, 2004;Wan et al, 2003). The bending term is usually considered (Elsner et al, 2006) as…”

Polymeric thin shells: Measurement of elastic properties at the nanometer scale using atomic force microscopy

“…Recently, fd curves have started to be used in combination with advanced optical microscopy methods to nanocompress micrometer-scale thin-shell structures such as cells [10] and polyelectrolyte multilayer microcapsules [11][12][13][14]. The nanocompression was executed by approaching the interrogated microstructure with a large-diameter (∼40 m) glass sphere glued at one side of a tipless AFM cantilever.…”

Multicompartmental Micro‐ and Nanocapsules: Hierarchy and Applications in Biosciences

“…The resulting CaCO 3 particles were co-precipitated with tetramethylrhodamineisothiocyanate (TRITC)-human serum albumin (HSA) and magnetite nanoparticles. This precursor was further coated with five bilayers of polyelectrolyte using the layer-by-layer (LbL) deposition technique [8][9][10][11][12][13][14][15] by alternating the adsorption of negative PSS (poly(sodium 4-styrenesulfonate); M w ¼ 70 kDa) and positive PAH (poly(allylamine hydrochloride);…”

“…[8][9][10][11][12][13][14][15][16][17] They are fabricated using the layer-by-layer technique [18][19][20][21][22][23][24] by coating colloidal templates followed by core dissolution. Polyelectrolyte microcapsules have evolved from just experimental exploration to structures capable of delivering different types of molecules, therapeutic agents for delivery, and for diagnostic assays within their interior or on their surface.…”