The present investigation analyses the mechanical behaviour of concrete with recycled aggregates from precast debris and waste glass. The combination of both recycled materials permits an increased amount of recycled coarse aggregates reducing the loss of mechanical performance of the concrete, and enhances the environmental value of the final material. Four variables are considered: the percentage of recycled course aggregates, the amount of mortar adhered to their surface, the amount of cement replaced by recycled glass powder and the maximum particle size. The final goal is to determine the significance of each variable in the final product and identify the most efficient combination to optimize the performance of the concrete, maximizing its environmental value. Significant results have been obtained, showing that the calibration of the parameters may not be trivial.